Welcome to the ISCB Community News Blog

This blog collects news, announcements or other information which could be of interest to our ISCB members. We are a group ISCB members who volunteer to populate this blog on a regular basis. In case you want to become an "ISCB-News Reporter" yourself, let us know: contact ISCB
Don't repost copyrighted content! The guidelines are:
- Include a link to the source page
- Include a short summary about the article. You can quote up to ONE paragraph from the original story, but not more
- Don't repost an entire articles originating from another source
- Never post content without attribution — always include the source

To post a news, please use this form.

Thursday, March 19, 2015

Training Workshops in Bioinformatics and Omics

The Institute for Genome Sciences (IGS) is an internationally known research center located at the University of Maryland School of Medicine in Baltimore. IGS offers five different workshops as part of a professional development program organized by Dr. Michelle Giglio, a faculty member at IGS with over 17 years of experience in genomics and bioinformatics. Dr. Giglio has recruited IGS faculty and staff to form a highly experienced instruction team to provide workshop participants with the knowledge and skills needed to engage in numerous omics applications. All IGS workshops are hands-on, providing attendees with real-world challenges and experience.

Please see our workshop dates listed below.


Metagenome Analysis
October 13th – 16th, 2015

Transcriptome Analysis
May 18th – 20th, 2015

Prokaryotic Comparative Genomics
September 29th – October 1st, 2015

Introduction to Genomics and Bioinformatics
November 2nd – 6th, 2015


Renée Nathaniel
Workshop Administrative Coordinator

URL: http://www.igs.umaryland.edu/education/workshops.php

Contact Person: Renee Nathaniel (rnathaniel@som.umaryland.edu)

Tuesday, March 17, 2015

NIGMS Strategic Plan Now Available

The new NIGMS strategic plan is now available at: http://publications.nigms.nih.gov/strategicplan. We would like to thank all of you who provided input to help shape this document, which outlines many of the priorities and activities that we will pursue over the next 5 years. The plan is designed to serve as a framework to both codify and focus our efforts, while still allowing us the flexibility to pursue untapped opportunities in mission-relevant areas.

In addition to its specific goals, objectives, and implementation strategies, the plan reiterates our commitment to the stewardship of taxpayer funds and an atmosphere of open dialogue, collaboration and shared responsibility with the scientific community. We welcome any suggestions you may have that would help us become as efficient and effective as possible in the pursuit of our mission.
URL: http://publications.nigms.nih.gov/strategicplan/NIGMS-strategic-plan.pdf

Contact Person: Richard Aragon, Ph.D. (richard.aragon@nih.gov)

Wednesday, March 11, 2015

CFP: Workshop on Evolutionary Computation in Computational Structural Biology at ACM GECCO 2015

The focus of this workshop is the use of nature-inspired approaches to central problems in computational structural biology, including optimization methods under the umbrella of evolutionary computation. A particular emphasis will be on progress in the application of evolutionary computation to problems related to any aspects of protein structure modeling, characterization, and analysis.

The workshop will allow for a broader focus on all structure-related problems that necessitate the design of novel evolutionary computation approaches. These may include broader structure modeling settings beyond de novo structure prediction, such as mapping of protein and peptide energy landscapes, structure analysis, design, docking, and other emerging problems in computational structural biology.

We invite submissions on presentations of the
following topics:

Use of artificial life models like cellular automata or Lindenmayer systems in the modeling of biological problems.

Study and analysis of properties of biological systems like self-organization, emergent behavior or morphogenesis.

Multi-objective approaches in the modeling of computational biology problems.

Use of natural and evolutionary computation algorithms in protein structure classification and prediction (secondary and tertiary).

Mapping of protein and peptide energy landscapes.

Modeling of temporal folding of proteins.

Protein design

Protein-ligand and protein-protein docking.

For more information, visit: http://eccsb2015.irlab.org/
URL: http://eccsb2015.irlab.org/

Contact Person: Amarda Shehu (amarda@gmu.edu)

Tuesday, March 10, 2015

Nominations for the National Medals of Science and National Medals of Technology and Innovation

Nominations are currently being accepted for the National Medal of Science and National Medal of Technology and Innovation. The National Medals offer a unique opportunity to showcase the best and brightest minds within your organizations and the outstanding scientists and innovators you work with each and every day.

to submit a nomination for the National Medal of Science, go to: https://www.fastlane.nsf.gov/honawards/medalHome.do;jsessionid=3252526f6b085051de1479869ce2:Dqk3
to submit a nomination for the National Medal of Science.

To download the nomination form for the National Medal of Technology and Innovation, go to: http://www.uspto.gov/learning-and-resources/ip-programs-and-awards/national-medal-technology-and-innovation-nmti

URL: http://www.nsf.gov/od/nms/nominations.jsp

Contact Person: Fae M. Jencks (Fae_M_Jencks@ostp.eop.gov)

Monday, March 9, 2015

PLOS Computational Biology 2014 Reviewer Thank You

The Public Library of Science (PLOS) and the PLOS Computational Biology editorial team would like to express our tremendous gratitude to all those individuals who participated in the peer review process this past year at PLOS Computational Biology. As a journal that is run by and for the scientific community, we depend upon you, the community, to communicate our best work. 2014 was great year for PLOS Computational Biology; during the year, over 2700 reviewers from around the world helped evaluate over 1000 articles.

The names of our 2014 reviewers are listed in S1 Reviewer List. Thank you to all our reviewers for sharing your expertise with the PLOS Computational Biology authors. Your efforts are an important part of making the journal a highly valued open access resource created by and for the benefit of the scientific community.
URL: http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004184

Contact Person: PLOS Computational Biology (alerts@e.plos.org)

Friday, March 6, 2015

The FAceS Project Survey

As part of the FAceS project (www.faces.wi.tum.de/), the Chair for Strategy and Organization (Prof. Isabell M. Welpe) at the Technische Universität München, Germany, is currently conducting a survey about publication practices and performance measurement in science. To attain representative knowledge about publication practices and performance measurement across different countries and disciplines (e.g., biology), we are particularly interested in your assessment and specifications on this topic. Participation in this survey will take approximately 20 minutes. Participants will be offered the chance to participate in the raffle for an iPad mini. Upon request, we will be happy to send you a summary of the results of the survey.

Survey URL: http://ww3.unipark.de/uc/OA/

Contact Person: Ringelhan, Stefanie (performance-management.lso.wi@tum.de)

Raymond and Beverly Sackler Support New NAS Prize for Convergence Research

WASHINGTON — The National Academy of Sciences announced today the creation of the new Raymond and Beverly Sackler Prize in Convergence Research. A generous gift from Raymond and Beverly Sackler and the Raymond and Beverly Sackler Foundation will endow the prize, to be presented annually beginning this year with an inaugural $400,000 award.

"The prize will recognize significant advances in convergence research -- the integration of two or more of the following disciplines: mathematics, physics, chemistry, biomedicine, biology, astronomy, earth sciences, engineering, and computational science -- for achievements possible only through such integration. This year's prize will be awarded for convergence research that benefits human health. Two-thirds of the prize money will be awarded to the selected researcher(s), and the remaining third will go to support the researcher's work.

"Convergence research is responsible for major breakthroughs that are making real impacts on people's lives such as 3-D printing of human tissue, new biofuels, and more precise drug delivery systems," said Raymond Sackler. "Beverly and I hope that the recognition and prestige bestowed through this prize encourages more researchers to work across disciplines and make exciting new discoveries."

"Convergence science is not only necessary but critical to tackling some of the world's most pressing challenges," said National Academy of Sciences President Ralph J. Cicerone. "This generous gift allows the National Academy of Sciences to highlight and support the revolutionary advances in science that result from interdisciplinary ideas and approaches."

Dr. Raymond Sackler is a founder and board member of Purdue Pharma L.P., Stamford, Conn., and the Mundipharma Companies of Europe, Asia and Africa. Individually and through their foundations, Dr. Sackler and his wife Beverly have sponsored scientific and biomedical research at a number of major U.S. academic centers, including: Boston University; CalTech (in collaboration with University of California, Los Angeles); Columbia University; Dana Farber Research Institute; Duke University; Institute for Advanced Study (Princeton); Massachusetts Institute of Technology; MD Anderson Cancer Center; Memorial Sloan-Kettering Cancer Center; New York University; Rockefeller University; Tufts University; University of California, Berkeley (in collaboration with University of California, San Francisco); University of Connecticut; University of Toledo College of Medicine; University of Washington, Seattle; Weill Cornell Medical School; Yale University; and the Harvard-Smithsonian Center for Astrophysics. International academic centers include Cambridge University (UK), Institut des Hautes Etudes Scientifiques (France), Tel Aviv University (Israel); University of Leiden (Netherlands); and the University of Toronto (Canada).

The National Academy of Sciences is a private, nonprofit institution that was established under a congressional charter signed by President Abraham Lincoln in 1863. It recognizes achievement in science by election to membership, and -- with the National Academy of Engineering, Institute of Medicine, and National Research Council -- provides science, technology, and health policy advice to the nation.

URL: http://www.national-academies.org/newsroom

Contact Person: Molly Galvin, Senior Media Relations Officer (news@nas.edu)

Wednesday, February 25, 2015

16th International Conference on Density Functional Theory and its Applications

The 16th International Conference on Density Functional Theory and its Applications is going to take place in Debrecen, Hungary, August 31- September 4, 2015. It will be the following in a series of biennial meetings, which have taken place in Paris (1995), Vienna (1997), Rome (1999), Madrid (2001), Brussels (2003), Geneva (2005), Amsterdam (2007), Lyon (2009), Athens (2011) and Durham (2013).

DFT2015 covers a wide range of topics related with density functional theory. It brings together researchers from all around the world working on the development of the theory, extensions to new fields and providing a broad range of fascinating applications including biomolecular modeling, bio­reactions.
URL: http://dft2015.unideb.hu/home

Contact Person: Professor A. Nagy (anagy@phys.unideb.hu)

Tuesday, January 20, 2015

The DREAM9.5 Challenges

We are pleased to announce that the DREAM Olfaction Prediction Challenge, the first of the DREAM9.5 Challenges is now open for participation. This Challenge focuses on predicting behavioral responses to a panel of odors, and features a first-of-its-kind dataset. To learn more and join this Challenge, go to: https://www.synapse.org/#!Synapse:syn2811262.

Besides joining the Olfaction Prediction Challenge, you can also pre-register for one or more of the other 9.5 Challenges in preparation. In this way we can keep you informed about the readiness of these three Challenges for participation.

Best performers from the DREAM9.5 Challenges will be invited to present at the DREAM Conference (Nov 16, 2015, Philadelphia, PA, USA) with travel expenses covered by the DREAM/Sage organizers. DREAM and Sage Bionetworks are also working with high impact journals to ensure that the methodology developed by the Challenges' best performers will be considered for publication under the Challenge-assisted Peer Review format

The DREAM9.5 Challenges

1) DREAM Olfaction Prediction Challenge: OPEN ·
* Challenge Focus: Predict behavioral responses to a panel of odors
* Join the Challenge: https://www.synapse.org/#!Synapse:syn2811262

2) Prostate Cancer DREAM Challenge. Launch Target: Late February, 2015
* Challenge Focus: Predict survival for prostate cancer patients based on patients' clinical variables
* Learn more and pre-register for this Challenge: https://www.synapse.org/#!Synapse:syn2813558

3) ICGC-TCGA DREAM Somatic Mutation Calling Tumor Heterogeneity Challenge (SMC-Het): Launch Target: Early March, 2015
* Challenge Focus: Identify the best subclonal reconstruction algorithms and to identify the conditions that affect their performance.
* Learn more and pre-register for this Challenge: https://www.synapse.org/#!Synapse:syn2813581

4) ICGC-TCGA DREAM Somatic Mutation Calling RNA Challenge (SMC-RNA): Launch Target: TBA
* Challenge Focus: Benchmark approaches for the calling of various types of RNA mutations and splice variants
* Learn more and pre-register for this Challenge: https://www.synapse.org/#!Synapse:syn2813589

To learn more about DREAM and Sage Bionetworks please go to http://dreamchallenges.org/ and http://sagebase.org

URL: http://dreamchallenges.org/

Contact Person: Gustavo Stolovitzky (gustavo@us.ibm.com)

Thursday, January 15, 2015

ISCB Fight against Ebola Award

Speed is of the essence in combating Ebola; thus, computational approaches should form a significant component of Ebola research. As for the development of any modern drug, computational biology is uniquely positioned to contribute through comparative analysis of the genome sequences of Ebola strains as well as 3-D protein modeling. Other computational approaches to Ebola may include large-scale docking studies of Ebola proteins with human proteins and with small-molecule libraries, computational modeling of the spread of the virus, computational mining of the Ebola literature, and creation of a curated Ebola database.

Taken together, such computational efforts could significantly accelerate traditional scientific approaches. In recognition of the need for important and immediate solutions from the field of computational biology against Ebola, the International Society for Computational Biology (ISCB) announces a prize for an important computational advance in fighting the Ebola virus. ISCB will confer the ISCB Fight against Ebola Award, along with a prize of US$2,000, at its July 2016 annual meeting (ISCB Intelligent Systems for Molecular Biology (ISMB) 2016, Orlando, Florida).
URL: http://f1000research.com/articles/4-12/v1

Contact Person: Diane Kovats (dkovats@iscb.org)

Wednesday, January 14, 2015

FASEB Releases Sustaining Discovery in Biological and Medical Science

This week, the Federation of American Societies for Experimental Biology (FASEB) released an analysis of the threats to continued progress in biological and medical science research. Sustaining Discovery in Biological and Medical Science: A Framework for Discussion examines the challenges facing researchers and presents a series of recommendations to alleviate them.

Sustaining Discovery in Biological and Medical Science: A Framework for Discussiondocuments how shortfalls in federal funding and rising regulatory costs have constrained research budgets. At the same time, scientific opportunities have expanded and more individuals are seeking funding. These opposing trends have resulted in an increasingly unstable research enterprise, delaying scientific discovery.

In the newly released statement, FASEB offers three broad categories of recommendations for consideration:

· Increased advocacy for predictable, sustainable growth in research budgets while striving to make optimal use of existing resources
· Re-examination of the way research is funded, making certain that we provide incentives to encourage the best science and reduce the amount of time spent seeking funding, and
· Improved preparation and utilization of the workforce.

To facilitate feedback from the members of FASEB societies and the broader research community, FASEB has created a website for reviewing the document and recording comments.

FASEB is composed of 27 societies with more than 120,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.
URL: http://faseb.org

Contact Person: Lawrence Green (lgreen@faseb.org)

Friday, January 9, 2015

Science Insider Story About Sustaining Discovery

An article on the Sustaining Discovery discussion framework was posted this morning: http://news.sciencemag.org/biology/2015/01/largest-u-s-biomedical-research-society-weighs-nih-s-budget-woes

The Sustaining Discovery website is now live at http://www.faseb.org/SustainingDiscovery/Home.aspx
URL: http://www.faseb.org

Contact Person: Howard H. Garrison, Ph.D. (info@faseb.org)

Thursday, January 8, 2015

FASEB Releases Its Newest Publication in the Horizons in Bioscience Series

Bethesda, MD – The Federation of American Societies for Experimental Biology (FASEB) is pleased to announce the release of the latest publication in the Horizons in Bioscienceseries, "Nanomedicine: A Targeted Approach." The article describes the emerging field of nanoparticle targeting.

Nanomedicine is beginning to change the way scientists and physicians diagnose and treat disease. Unlike conventional therapies, these tiny particles – 1,000 times smaller than the diameter of a human hair – can seek out diseased tissue and access hard to reach places in the body. This article will provide readers with an understanding of what nanoparticles are, how they specifically target diseased tissue, and how they can diagnose and treat some of our most devastating diseases.

The Horizons in Bioscience series is a collection of short, illustrated articles published by FASEB that describe scientific discoveries on the brink of clinical application. Printed copies of the articles are available at no cost for educational or advocacy purposes and can be requested by visiting the Breakthroughs in Bioscience website at www.faseb.org/breakthroughs or by contacting FASEB's Office of Public Affairs at 301-634-7650.
URL: http://www.faseb.org/pdfviewer.aspx?loadthis=http%3A%2F%2Fwww.faseb.org%2FPortals%2F2%2FPDFs%2Fopa%2F2015%2Fnanoparticles%2520horizons%2520article.pdf

Contact Person: Lawrence Green (mailto:lgreen@faseb.org)

Monday, January 5, 2015

RECOMB 2015 Call for Posters and Highlights

RECOMB 2015 (http://www.recomb2015.pl ) invites the submission of abstracts of papers that have been published in a journal after October 1, 2013 or papers that are "in press" at the time of submission and are already linked on the journal web site.

"Highlight" papers can be submitted to the main RECOMB conference as well as to the satellite meetings RECOMB-seq and RECOMB-ccb (http://www.recomb2015.pl/satellite-meetings ). The papers will be selected for presentation by taking into consideration the impact of the work on the field, the likelihood that the work will make a good presentation and the relevance to biological and biomedical research in general.

Please visit https://www.easychair.org/conferences/?conf=recomb2015 to submit your abstract. Submissions must contain an abstract (about 200 words, plain justified text in 10pt character size, formatted to fit A4: 21 x 29.7 cm, including title, author(s), affiliation, e-mail, a link to the published journal version, the identity of the presenter (in case of a multi-authored paper), the name of the meeting(s)submitted to in order of preference (i.e., RECOMB, RECOMB-seq, or RECOMB-ccb) followed by the abstract text. Abstracts lacking this information will not be considered. Accepted presenters for the Highlight Track are required to make the presentation themselves, and must register and pay to attend the conference.

Key dates
Submission deadline: January 15, 2015
Acceptance notification: January 31, 2015

Please also be aware that RECOMB 2015 allows presentation of your work in a poster session. The poster abstract submission is handled by tha same website and the submission deadline is February 15th.

More information can be found on the RECOMB 2015 website: http://www.recomb2105.pl

URL: http://www.recomb2015.pl

Contact Person: Bartek Wilczynski (bartek@mimuw.edu.pl)

Monday, December 15, 2014

Dragonflies on the Hunt Display Amazing Choreography

The dragonfly is a swift and efficient hunter. Once it spots its prey, it takes about half a second to swoop beneath an unsuspecting insect and snatch it from the air.

Scientists at the Howard Hughes Medical Institute's Janelia Research Campus have used motion-capture techniques to track the details of that chase, and found that a dragonfly's movement is guided by internal models of its own body and the anticipated movement of its prey. Similar internal models are used to guide behavior in humans. The work is published in Nature.
URL: http://www.hhmi.org/news

Contact Person: HHMI News (webmaster@hhmi.org)

Monday, December 8, 2014

FASEB Announces 2016 Excellence in Science Award Nomination Season


FASEB is seeking nominations for its 2016 Excellence in Science Award that recognizes the significant accomplishments of women scientists. We look forward to another list of nominees that reads like a 'Who's Who' of international science, containing the names of outstanding women in science who have accomplished scientific work of lasting impact and have contributed substantially to training the next generation of scientists.

The Excellence in Science Award recognizes outstanding achievement by women in biological science. All women who are members of one or more of FASEB Member Societies will be eligible for nomination. Nominations recognize a woman whose career achievements have contributed significantly to further our understanding of a particular discipline by excellence in research.


Nomination Procedures:
Nominators and their candidates must be members of at least one FASEB Member Society but do not have to be members of the same society. Self-nominations will not be accepted. All nominations must be submitted on the FASEB nomination form (available on the FASEB website). Access to the site will be available as of January 1, 2015.

Nominees will be evaluated on the following criteria:
· Scientific achievements including landmark discoveries, high impact publications, and scientific leadership
· Training of students and postdoctoral fellows including impact on careers and teaching efforts
· Contributions to the broader scientific community, such as leadership in professional organizations, university service and leadership, and public outreach

Nomination Procedures:
Nominators and their candidates must be members of at least one FASEB Member Society but do not have to be members of the same society. Self-nominations will not be accepted. All nominations must be submitted on the FASEB nomination form (available on the FASEB website). Access to the site will be available as of January 1, 2015.
Nomination letter, setting forth in detail:

· Contributions to the field that represent the nominee's outstanding achievement in science
· Evidence of leadership
· Evidence of mentorship
· Evidence of national recognition
· Honors and awards
· Synopsis of selected bibliography
Complete curriculum vitae documenting:

All publications
Leadership roles
Honors and recognition
Grant awards
Five nominee reprints demonstrating most significant contributions
Three letters of support from the nominee's peers illustrating impact on the field
Three letters of recommendation from trainees illustrating mentorship and impact on careers
URL: http://www.faseb.org/About-FASEB/Awards/Excellence-in-Science-Award.aspx

Contact Person: Linda Stricker (lstricker@faseb.org)

Wednesday, November 26, 2014

Cytoscape Team at RSGw/DREAM

The Cytoscape team was thrilled to be a part of this year's Regulatory and Systems Genomics conference along with DREAM Challenges. Thanks to support from the National Resource for Network Biology (http://nrnb) and Agilent Technologies, we were able to host a number of unique events integrated into the meeting. The week started off with a sold-out Cytoscape workshop for new users, and a parallel workshop for Cytoscape app developers. These workshops included an introduction to network biology approaches, hands-on sessions with the latest Cytoscape 3.2.0 release, and professional app development training. The next day we shared a well-attended Cytoscape poster session with DREAM Challenges, mixing two communities of like-mined researchers. Finally, during the Systems Biology track, we integrated two Cytoscape App Expo sessions. Each session consisted of four 10-minute presentation about new Cytoscape Apps and how to apply them to systems biology research. All in all, a hugel y successful event with lots of great interactions. Thanks again to the RECOMB and ISCB co-organizers!
URL: http://gladstoneinstitutes.org

Contact Person: Alexander Pico, PhD (apico@gladstone.ucsf.edu)

Wednesday, November 19, 2014

A 45,000-Year-Old Leg Bone Reveals The Oldest Human Genome Yet

Researchers have successfully decoded the genes of a 45,000-year-old man from Siberia. The results offer clues about early human life outside of Africa as well as how humans interacted with Neanderthals and other groups around at the time.

The complete set of genes is the oldest genome of its kind, according to Svante Pääbo, a director at the Max Planck Institute for Evolutionary Anthropology in Leipzig. "It's almost twice as old as the next oldest genome that has been sequenced."

The work of Pääbo and his colleagues was published Wednesday in the journal Nature.

The DNA came from a human femur found in 2008 by a collector scouring the Irtysh River in western Siberia. The femur was handed over to a local paleontologist who in turn gave it to Pääbo's team in Leipzig.

When the age of the bone was revealed, the team couldn't believe it. "We were actually so amazed, we actually had it dated even twice, to make sure," Pääbo says.

Pääbo's team specializes in extracting ancient DNA from bones like these. They carefully set to work retrieving genetic material from bone cells in the femur. Because the bone came from a modern human, they had to take precautions to ensure it wasn't contaminated with their own genetic material.

The results provide a window into an unusual period in human existence.

Modern humans evolved in Africa around 200,000 years ago. They left the continent around 100,000 years ago. But researchers now know that other human-like people were already living in Europe and Asia. These included Neanderthals, large, muscular hominins that lived in the caves of Europe.

"What's exciting about this paper is that it's looking at a very ancient modern human who would have lived around the same time as Neanderthals," says Sarah Tishkoff, a geneticist at the University of Pennsylvania who was not involved with the work.

The bone shows that the Siberian man's DNA contained a tiny amount of Neanderthal genes. In other words, he had some Neanderthal ancestors. It's the latest in a series of papers showing that humans and Neanderthals bred.

Modern Asians, Europeans and Native Americans also have Neanderthal genes, but the Neanderthal gene sequences of the Siberian man were longer, indicating that interbreeding had taken place in the relatively recent past, between 50,000 and 60,000 years ago.

"They actually mixed with each other and did have children," Pääbo says.

As intriguing as the bone is, it leaves many questions about what happened next.

We know that humans thrived and that Neanderthals eventually went extinct, but we still don't know why, says Janet Kelso, a computational biologist at the Max Plank Institute in Leipzig, and a co-author on the paper. "The genetics just doesn't tell us anything about that."

Just as big a mystery is what happened to the Siberian man and his descendants.

Previously it was thought ancient humans hadn't lived so far north 45,000 years ago. And venturing into the region may have been a bad move, Pääbo suspects. The Siberian man's genetic code is distant from other groups of humans, suggesting his family may have gone extinct even before Neanderthals died out.
URL: http://www.npr.org/blogs/health/2014/10/22/358047524/a-45-000-year-old-leg-bone-reveals-the-oldest-human-genome-yet

Contact Person: Geoff Brumfiel (GeoffBrumfiel@npr.org)

Tuesday, November 11, 2014

ISCB announces 2015 Journal Subscriptions now available to ISCB Members

ISCB members can now subscribe to the 2015 issues of our Community Journal at discounted prices:

* Bioinformatics; ISCB Members receive a substantial discount, for more information click here
* Briefings in Bioinformatics Online and Print Discounts available to ISCB Members, for more information click here
* Briefings in Functional Genomics & Proteomics Online and Print Discounts available to ISCB Members for more information, click here
* Computers in Biology and Medicine Online and Print Discounts available to ISCB Members, for more information click here
* Computer Methods and Programs in Biomedicine Online and Print Discounts available to ISCB Members, for more information click here
* Human Molecular Genetics Online and Print Discounts available to ISCB Members, for more information click here
* Journal of Biomedical Informatics Online and Print Discounts available to ISCB Members, for more information click here
* Journal of Computational Biology Online Discount is available to ISCB members. for more information click here

Current members just login to your ISCB membership and select "Subscribe to Journals" from the menu on the left. New members can subscribe during their registration process.
URL: http://www.iscb.org

Contact Person: Suzi Smith (admin@iscb.org)

Wednesday, November 5, 2014


Athens, GA - The Computational Systems Biology Lab of the University of Georgia's department of biochemistry and molecular biology is pleased to announce the release of "Cancer Bioinformatics" by Springer.  Authors Ying Xu (UGA), Juan Cui (University of Nebraska, Lincoln) and David Puett (UGA, retired) provide a framework for computational researchers studying the basics of cancer through comparative analyses of omic data. The book discusses how key cancer pathways can be analyzed and discovered to derive new insights into the disease and identifies diagnostic and prognostic markers for cancer.
Cancer has been typically studied at the cell level or with xenografted animals, outside of the microenvironmental stresses and pressures that shaped the development of the cancer.  This approach assumes that cancer will develop following the known rules of human biology.  Instead the authors leveraged the data from The Cancer Genome Atlas and found that cancer biology is fundamentally different from human biology.  Their book outlines a radically new framework for basic cancer biology, how cancer develops, and the many paths it can take to survive.  The authors also treat cancer as an evolving complex system, explore future case studies, and summarize the essential online data sources.
"Cancer Bioinformatics" is designed for practitioners and researchers working in cancer research and bioinformatics. It is also suitable as a secondary textbook for advanced-level students studying computer science, biostatistics or biomedicine.  You can access an online book review copy at no cost by visiting the book's web page at http://www.springer.com/computer/bioinformatics/book/978-1-4939-1380-0 and listen to a short podcast of lead author Ying Xu talking about cancer and hypoxia on WAMC's Academic Minute - http://academicminute.org/2014/10/ying-xu-university-of-georgia-hypoxia/. 
The CSBL is a part of UGA's Franklin College of Arts and Science department of biochemistry and molecular biology and is dedicated to developing a new framework studying cancer and in doing so enable other cancer researchers and computational biologists to join in and contribute.

URL: http://csbl.bmb.uga.edu/
Contact Person: Heather Jensen (hjensen@uga.edu)

Tuesday, November 4, 2014

IJCB: Call for papers

International Journal for Computational Biology (IJCB), which provides a rapid forum for the dissemination of original research articles as well as review articles in all areas of Computational Biology and Bioinformatics invites manuscripts. IJCB is a n official journal of Bioclues Organization, which in turn is an associate of ISCB.

International Journal for Computational Biology is published using an open access publication model, meaning that all interested readers are able to freely access the journal online at http://www.ijcb.in/ without the need for a subscription.

We are maintaining a mirror repository at www.bioinformatics.org for round the clock hassle free readership. Further we are in process of getting indexed with most of the world class citation and indexing databases for better impact and visibility of your research work.

The journal has a distinguished editorial board with extensive academic qualifications, ensuring that the journal maintains high scientific standards and has a broad international coverage. A current list of the journal\\\'s editors can be found at journal website.

Paper should be submitted through online manuscript submission system (Details of which has been given on journal website). Once a paper has been accepted for publication, it will undergo language copyediting, typesetting, and reference validation in order to provide the highest publication quality possible.

Please do not hesitate to contact me if you have any questions about the journal.

With kind regards

International Journal for Computational Biology (ISSN: 2278-8115)
Web: http://www.ijcb.in/
Email: ijcb@bioclues.org
URL: http://www.ijcb.in/

Contact Person: Chief Editor (ijcb@bioclues.org)

Friday, October 31, 2014

Call for Applications: Research Collaboration Workshop for Women in Mathematical Biology

The National Institute for Mathematical and Biological Synthesis (NIMBioS) is now accepting applications for the Research Collaboration Workshop for Women in Mathematical Biology, to be held June 22-25, 2015, at NIMBioS.

Objectives: This collaborative workshop aims to help build a strong collaboration network of women working on problems in mathematical biology, by facilitating the formation of new collaborative research groups and encouraging them to continue to work together after the workshop. Junior women (tenure track faculty, post-docs and advanced graduate students) in biology, mathematics and related fields are encouraged to apply. The format of this workshop is designed to maximize the opportunities to collaborate:

There will be four teams. Each team will be led by two senior women researchers and will work collaboratively on a specific project. Team members will be chosen from applicants and will consist of junior researchers from both mathematics and biology. Team members can express their project preference in their application Each team will work intensely and present their findings at the end of
the workshop.

Each team is expected to continue their research and obtain results for a joint publication.

Projects: Aerodynamics of spider ballooning; sleep, circadian rhythms and pain; blood flow autoregulation in the kidney; and modeling the effects of antimicrobial therapy on gut microbiota and Clostridium difficile

Location: NIMBioS at the University of Tennessee, Knoxville

Co-Organizer: Anita Layton, Mathematics, Duke Univ.

For more information about the workshop and a link to the online application form, go to http://www.nimbios.org/education/WS_wwmb.html

Participation in the workshop is by application only; 3-4 participants will be selected for each team. Successful applicants will be notified within two weeks of the application deadline. If needed, financial support for travel, meals, and lodging is available for workshop attendees.

Application deadline: March 1, 2015

The National Institute for Mathematical and Biological Synthesis (NIMBioS) (http://www.nimbios.org) brings together researchers from around the world to collaborate across disciplinary boundaries to investigate solutions to basic and applied problems in the life sciences. NIMBioS is sponsored by the National Science Foundation, with additional support from The University of Tennessee, Knoxville.
URL: http://www.nimbios.org

Contact Person: Catherine Crawley, Ph.D. (ccrawley@nimbios.org)

Thursday, October 30, 2014

Top 10 papers reading list for 2013-14: call for nominations

Dear Colleagues,

Please help nominate papers in the field of Regulatory and Systems Genomics, that you've recently read and found to be of particular interest. Relevant areas include Motifs, Grammars, Networks, Systems, Variation, Disease, Personal Genomics, GWAS interpretation, Regulatory Evolution, Comparative genomics, Epigenomics, Physical modeling, Dataset Integration, Splicing regulation, transcriptional regulation, and all areas of gene and genome regulation at the systems level.

You can find the nomination form here: http://goo.gl/forms/ENlRYpOVhD

Please nominate papers that appeared between September 1st, 2013 and August 31st, 2014. You can of course nominate a paper from your own group, but we ask that if you are doing so, to also take the time to nominate at least one paper that was not co-authored by you.

The nomination process will close on November 5th.

Our goal is to identify seminal papers that introduced not only new biological insights, but also key computational methodologies for interpreting biological datasets that have had and will continue to have a lasting impact in the field of Regulatory and Systems Genomics. These will be honored at an awards ceremony in the 2014 RECOMB/ISCB Meeting on Regulatory and Systems Genomics in San Diego on November 9-14, 2014. http://www.iscb.org/recomb-regsysgen2014

Thank you for your help and for being part of our community,

Manolis Kellis and Saurabh Sinha
Co-organizers, RegSysGen Top 10 Papers Reading List
ISCB Special Interest Group On Regulatory & Systems Genomics (RegSys SIG)
URL: http://cosi.iscb.org/wiki/RegSIG:Home

Contact Person: Manolis Kellis (sinhas@illinois.edu)

Tenth Annual Great Lakes Bioinformatics Conference : GLBIO 2015

Tenth Annual Great Lakes Bioinformatics Conference : GLBIO 2015

An official conference of the International Society for Computational Biology. Organized by the Great Lakes Bioinformatics Consortium. Co-hosted by Purdue University and the International Society for Computational Biology

The Great Lakes Bioinformatics Conference:
~ Provides an interdisciplinary forum for the discussion of research findings and methods.
~ Fosters long-term collaborative relationships and networking opportunities within the domain of computational approaches to biology.

GLBIO has established a strong reputation for building relationships among a nationally prominent bioscience research community, showcasing the North American Great Lakes region as a perfect place to conduct computer-aided research.

Every year, GLBIO organizers prepare a full agenda on the latest developments in bioinformatics and biologically relevant applications. From novice to expert, attendees partake in a variety of workshops, tutorials, presentations, posters, networking, and exhibits during the conference. 2015 program outline:

Monday, May 18: Afternoon tutorials and opening keynote

Tuesday, May 19 and Wednesday, May 20 : All day education including keynote speeches by

Bioinformatics community leaders, cutting edge research through poster sessions and tutorials on a variety of hot topics.
GLBIO 2014 was 2.5 days and consisted of the following presentations:
7 keynotes 7 tutorials
12 highlights talks 9 research talks 13 flash talks
102 poster presentations, presented in two sessions
1 educational panel 1 career symposium 1 sponsored tech talk

The most popular topics included scientific talks on the following topics:
• Applying bioinformatics approaches to further develop medical treatments for cancer Ecological bioinformatics
• Gene expression studies
• Genomic analysis and discovery and pathway analysis
• Machine learning
• Protein structures

Check out the latest schedules and updates at www.iscb.org/glbio2015

URL: http://www.iscb.org/glbio2015

Contact Person: Cori Dossett (glbio@conferencesdesigned.com)

Tuesday, October 28, 2014

Special Issue on Advances in Computational Methods for Genetic Diseases : Extended deadline

Due to Publisher policy, the deadline for the submission of papers has been extended. The new Issue schedule is the following:
Manuscript Due Friday, 21 NOVEMBER 2014
First Round of Reviews, 13 FEBRUARY 2015
Publication Date, 10 APRIL 2015
URL: http://www.hindawi.com/journals/cmmm/osi

Contact Person: Antonino Staiano (antonino.staiano@uniparthenope.it)

Friday, October 24, 2014

Highlighting How Federally Funded Research Improves Health Ensures Continued Support for Science

FASEB Vice President for Science Policy Hud Freeze, PhD, is driven by the search for new treatments for patients with rare genetic diseases. Specific targets are mutations leading to defects called Congenital Disorders of Glycosylation (CDG). Dr. Freeze is equally passionate about the need to explain how finding cures starts with research to understand basic biological processes, much of which is funded by grants from the federal government. To ensure improved health, he and the FASEB leadership urge scientists to explain their work in public forums and to the media. Some examples of Dr. Freeze's efforts in this regard are linked here: 1) a San Diego TV show with a child suffering from a rare genetic disorder (http://link.brightcove.com/services/player/bcpid1649263564001?bckey=AQ~~,AAAAA5PNMME~,K3tOT-PuafsBOFardsNAXlIchcEkjy_p&bctid=3547868835001); and 2) a video from the Global Genes 2014 Rare Patient Advocacy Summit, session 9, from about minute 11 to 18:40 (http://globalgenes.org/2014summitvideos/).

Contact Person: Joseph Carey (jcarey@faseb.org)

NIH Group Analyzes Grant Processes at Other U.S. Agencies and in the United Kingdom

The National Institutes of Health (NIH) Scientific Management and Review Board (SMRB) on October 14 heard descriptions of the grant processes at other U.S. federal research agencies and at two funding organizations based in the United Kingdom.

Charged with providing guidance to the NIH Director on the organization of the NIH and the implementation of its funding portfolio, a SMRB Working Group since May has explored ways to streamline the grant review, award, and management process. Previous sessions featured presenters from NIH's Office of Extramural Research, the Center for Scientific Review, several NIH institutes and centers; and academic researchers with extensive service on peer review panels.

Sonny Ramaswamy, PhD, Director of the National Institute of Food and Agriculture at the U.S. Department of Agriculture (USDA) presented an overview of the grant-making arm of the agency and the average timelines for applications and awards. He said that the agency was struggling to find ways to shorten its process, which takes approximately 25 to 38 weeks on average. Dr. Ramaswamy flagged USDA's reliance on Requests for Applications (RFAs) or "solicited research" as a key difference between the NIH and USDA granting process, which adds approximately 14 to 16 weeks to the timeline to develop and announce the funding opportunity. Another key difference is that most USDA grants provide one year of funding, with some providing two years; NIH grants typically provide three to five years of support.

The National Science Foundation (NSF) grant review and award process, and potential expediting strategies, were discussed by the agency's Joanne Tornow, PhD, Deputy Assistant Director for Social, Behavioral, and Economic Sciences. She stated that 94 percent of NSF's FY 2013 budget went to extramural research. Of the 48,999 proposals received, the agency funded 10,829 new awards. Approximately three-quarters of all proposals are processed within six months of receipt, with potential bottlenecks caused by difficulty identifying reviewers, additional steps in the review process (e.g., site visit, review by the Director's Review Board or by the National Science Board, etc.), missing documentation, the agency processing a large volume of applications, or the uncertain status of the federal budget. Dr. Tornow noted that NSF has several pilot projects underway to test changes to specific aspects of the peer review process. These include virtual review panels and use of shorter preliminary proposals to reduce the number of full applications that need review.

Representatives of the U.K.'s Wellcome Trust and the Medical Research Council also described their grant processes. Both models incorporate face-to-face interviews with applicants in addition to written reviews.

Alyson Fox, PhD, Wellcome's Head of Grants Management, briefly described the application and review process for both its Investigator Awards, which are equivalent to the NIH R01 grant, and Intermediate Fellowships for postdoctoral scholars. Both processes take approximately 18 weeks with external reviewers engaged only after staff determine applications to be "shortlisted" for further review. During questions and answers, it appeared that this process would not be scalable to NIH, since Wellcome reviews only 160 to 180 applications per cycle for the Investigator Awards and 220 to 250 preliminary applications for the Intermediate Fellowship program.

Declan Mulkeen, PhD, Chief Science Officer for the Medical Research Council briefly described the approximately six month review process by which it funds 350 to 400 individual awards per year. Dr. Mulkeen noted that the process had been reduced from nine to 12 months by implementing shorter application forms and eliminating post-review resubmissions.
URL: http://

Contact Person: Yvette Seger (yseger@faseb.org)

News from NIH

The National Institutes of Health (NIH) recently released several notices of interest to the biological and biomedical research community, ranging from clarifying the role of graduate students and postdocs supported by research grants to the suspension of funding for certain types of research.

On October 10, NIH issued a notice that is particularly significant for postdoctoral scholars, the majority of whom are supported by research project grants. It recognizes their positions as both contributing to a research effort and as an opportunity to develop skills critical to becoming independent researchers. The notice reiterates the clarification released by the Council on Financial Assistance Reform (COFAR) and the Office of Management and Budget (OMB) regarding the dual role of graduate students and postdocs supported on federal research grants. The clarification states, "For non-Federal entities that educate and engage students in research, the dual role of students as both trainees and employees contributing to the completion of Federal awards for research must be recognized in the application of these principles."

An NIH Request for Information (RFI), also issued on October 10, seeks public input to inform the development of a program to facilitate the transition of physician-scientists to independent research careers. Proposed options include: modification of existing mentored career development awards, restructuring of institutional training or career development awards to fulfill the specific needs of physician-scientists, and development of a K99/R00 career transition award that better suits the career trajectory of physician-scientists to obtain input on perceived barriers and possible solutions to reinvigorate this dwindling workforce. The document builds upon the findings and recommendations of the Physician-Scientist Workforce Working Group that was presented the Advisory Committee to the Director, NIH, in June. Responses must be submitted via the RFI website and are due by November 3, 2014.

In accordance with an October 17 statement from the White House, NIH announced a funding pause for new "gain-of-function research" involving influenza, MERS, and SARS viruses. The three viruses were selected because of the significant risk they pose to public health. NIH defines gain-of-function research as any modification of a biological agent — like viruses, bacteria, or toxins — that gives it new or enhanced activity. Research affected under this announcement is limited to projects using any of the three viruses that are anticipated to enhance their pathogenicity or transmissibility via the respiratory system in mammals. The funding pause, which is expected to last nine months, will not impede efforts to characterize or test naturally-occurring versions of these viruses. During the pause, the government will carry out a deliberative process to assess the risks and benefits of such studies and will develop a new Federal policy regarding the funding of this research .
URL: http://

Contact Person: Yvette Seger (yseger@faseb.org)

Friday, October 10, 2014

Survey on credible practice of modeling and simulation in healthcare

With this invitation, we are asking you to complete a survey aimed to establish good practice guidelines in order to realize credibility of computational modeling and simulation (M&S) in healthcare. The survey can be found at:


The survey site will be available until February 15, 2015.

We sincerely appreciate your participation in this survey, which should take no longer than 10 minutes. Your participation is voluntary and your responses will be anonymous. You have been identified as a potential stakeholder in the M&S community. Your support will be instrumental in developing broadly applicable best practices in M&S, for their ultimate utilization in healthcare.

This survey is an initiative of the Committee on Credible Practice of Modeling & Simulation in Healthcare, to understand global and multidisciplinary perspectives in best practices to establish credibility of computational medicine. The Committee was formed as part of interactions within the Interagency Modeling and Analysis Group (IMAG) and Multiscale Modeling Consortium, which provide a platform to facilitate discussions between federal agencies in the United States and investigators within the United States and worldwide.

Please feel free to forward this invitation to others that may have an interest in providing their insight. Thank you for your support. If you have any questions, please feel free to contact me by phone, +1 (216) 445 9523, or by e-mail, erdemira@ccf.org.



Ahmet Erdemir, PhD on behalf of Committee on Credible Practice of
Modeling & Simulation in Healthcare


Contact Person: Joy Ku (joyku@stanford.edu)

Wednesday, October 8, 2014

Call for Papers: Special issue on machine learning techniques in biological data mining

Dear colleague,

We invite you to submit a paper for a supplement to be published in Bioinformatics and Biology Insights in the next twelve months. The journal is extensively indexed and all published papers appear in Pubmed. The supplement focuses on current developments in machine learning techniques in biological data mining. In this supplement, we will discuss the use of machine-learning techniques to extract meaningful information from genetic and clinical data with the primary objective of answering pressing biomedical questions. Topics of interest include but are not limited to:

* Building predictive models for complex phenotypes from large-scale biological data
* Discovering biological networks and pathways underlying biological processes and diseases
* Processing of new/next-generation sequencing (NGS) data for genome structural variation analysis, discovery of biomarkers and mutations, and disease risk assessment
* Discovery of genotype-phenotype associations
* Novel methods and frameworks for mining and integrating big biological data
* Comparative genomics
* Metagenome analysis using sequencing data
* RNA-seq and microarray-based gene expression analysis
* Genome-wide analysis of non-coding RNAs
* Genome-wide regulatory motif discovery
* Correlating NGS with proteomics data analysis
* Functional annotation of genes and proteins
* Chemo-informatics: Drug discovery, Virtual screening and Combinatorial chemistry
* Knowledge discovery in clinical data and electronic medical records

If you are interested in contributing, please contact the guest editors Dr. Gaurav Pandey (gaurav.pandey@mssm.edu) and Dr. Gerard Dumancas (gerard.dumancas@okstate.edu) to discuss your contribution. In order to proceed, please submit a manuscript title and agreed submission date as soon as possible. Submissions must be received for peer review on or before June 1, 2015. We hope to hear from a lot of you!
URL: http://www.la-press.com/journal-bioinformatics-and-biology-insights-j39

Contact Person: Gaurav Pandey (pandey.gaurav@gmail.com)

Friday, October 3, 2014

Submission of manuscripts for publication

Journal of Biological and Food Science Research (JBFSR) with ISSN: 2277-0828 is currently accepting manuscripts for publication. JBFSR is an open access, international, multidisciplinary, blind peer-review journal which publishes high-quality solicited and unsolicited research and review articles in English, in all areas of bioinformatics, biology, microbiology, food science, botany, life science, biochemistry, optometry, zoology, industrial biology, industrial microbiology, clinical microbiology, laboratory science, cell and animal biology, genetics and molecular biology, medical sciences, dentistry, medical diagnosis and laboratory, computational biology, etc.

JBFSR is a rapid response journal that publishes an issue monthly. One of our objectives is to inform contributors (authors) of the decision on their manuscript(s) within a MONTH of submission. Following acceptance, a paper would be published in the next available issue. JBFSR provides immediate open access to published articles without any barrier.

Publishing your article with JBFSR means that the article will be available to millions of researchers in the field of Biological and Food Science Research because our large and diverse readership base comprises of millions of researchers. Majority of the journal's readers are academic lecturers, students, policy makers in the beverage industry, food and canning industry, and policy makers in government. Our journal support free downloading of published articles by scholars for use as materials for lecture, by government officials for policy making, and corporate researchers to favour corporate organizations world-wide. Also, JBFSR is a registered member of several local and international organizations? making it possible for the far and wide distribution of published articles. We ask you to support this initiative by publishing your paper(s) in this journal.

Authors should send their manuscript(s) as MS Word attachment to our editorial office through the following email address:
submit.jbfsr@onlineresearchjournals.org or
jbfsr.onlineresearch@yahoo.com; Instructions for authors and other details are available on our website www.onlineresearchjournals.org/JBFSR.
You may wish to visit
http://onlineresearchjournals.org/JBFSR/archive.htm for articles already published in this journal.
URL: http://www.onlineresearchjournals.org/JBFSR

Contact Person: Chairy Onyia (submit.jbfsr@onlineresearchjournals.org)

Thursday, October 2, 2014

Call for Bioclues Innovation, Research and Development (BIRD) awards for the year 2014

To encourage budding bioinformaticists in India who have had made outstanding contributions in the area of Bioinformatics and Functional Genomics, we have initiated the Bioclues Innovation, Research and Development (BIRD) awards in the year 2011. The call for the 2014 is now open. Do you have the following traits?

●Promoted international standards for R and D in India.

●Created novel models/opportunities or Bioinformatics-based tools.

●Mentored student researchers.

●S/he is less than 35 years and preferably a PhD in Bioinformatics or related field.

●Secured grants in organizing international events and activities in support of Bioinformatics.

●Have penchant for and respect Open Access

More at www.bioclues.org
URL: http://www.bioclues.org

Contact Person: Prashanth Suravajhala (prash@bioclues.org)

Friday, September 26, 2014

Computer method IMPACT-F replaces unreliable animal tests

Experiments in animals are used to estimate drug-uptake in humans. If drug-uptake in animals is too low, drug candidates are excluded from further development.

But large differences exist on drug-uptake between animals and humans. This also applies to very successful commercial drugs, called blockbuster drugs, with annual sales of more than one billion US Dollar.

Drug-uptake studies in animals are misleading: Aripiprazole and Esomeprazole, the most sold drugs of 2013, have low oral bioavailability in animals, but drug-uptake in humans is high.

The new expert system IMPACT-F replaces animal trials on drug-uptake.

Pharmaceutical companies have applied the expert system to evaluate human drug-uptake in various therapeutic areas such as diabetes, inflammation, antivirals, autoimmune diseases and cancer.

The expert system evaluates drug-uptake in humans significantly more reliably than animal trials. This further increases the prospects of human clinical trials, because the optimum oral dose for first-in-human clinical trials can be determined much more accurately.

Efficacy issues are identified as the main reason why clinical trials fail.

About PharmaInformatic:
The biotech company PharmaInformatic was founded in 2004 and provides ADME knowledge bases and predictive tools (expert systems) to improve drug discovery and development. The company is based in Germany.

Further detailed information:


URL: http://www.pharmainformatic.com

Contact Person: Dr. Wolfgang Boomgaarden (presse@pharmainformatic.com)

Friday, September 19, 2014

Extended deadline Special Issue: Advances in Computational Methods for Genetic Diseases

Special Issue - Advances in Computational Methods for Genetic Diseases - Computational and Mathematical Methods in Medicine, Hindawi

Due to potential authors requests, the deadline for the submission of papers has been extended. The new Issue schedule is the following:


Manuscript Due Friday, 19 OCTOBER 2014
First Round of Reviews Friday, 12 December 2014
Publication Date Friday, 6 February 2015


Genetic diseases are widely studied for the relevant impact on the human health. In the last years, a large amount of experimental data has been available. The identification of new strategies for elaborating such experimental data is becoming more and more necessary since the large amount of information can sometimes represent a real obstacle for the effective identification of relevant findings. The aim of the special issue is to review the recent advances about the research on computational methods concerning with genetic diseases. Potential topics include, but are not limited to:

Computational and mathematical methods for the following:
- Evaluating the pathogenicity of novel genetic variants
- The evaluation of protein folding and/or protein-protein interactions in presence of genetic variants
- Analysis of experimental data from next generation sequencing
- Searching for variant/mutation databases for massive data analysis
- Analysis of "omics" data
- Analysis of complex diseases, namely, multifactorial and polygenic, for example, diabetes, hypertension and dyslipidemia
- Variant analysis from Genome Wide Association studies
- Analysis of common genetic variants (i.e., SNPs, HLA genotypes, microsatellites)
- Analysis of quantitative trait loci
- The integration of genetic and non genetic factors for prediction of disease predisposition
- The identification of potential gene regulatory elements (i.e., binding of transcription factors, and miRNAs)
- Analysis of gene expression data
- Analysis of biological models of genetic diseases

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/cmmm/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/cmmm/genet/

URL: http://www.hindawi.com/journals/cmmm/si/828505/cfp/

Contact Person: Antonino Staiano (antonino.staiano@uniparthenope.it)
URL: http://www.hindawi.com/journals/cmmm/osi/

Contact Person: Antonino Staiano (antonino.staiano@uniparthenope.it)

Tuesday, September 2, 2014

Last call for papers: Advances in Computational Methods for Genetic Diseases

Special Issue - Advances in Computational Methods for Genetic Diseases - Computational and Mathematical Methods in Medicine, Hindawi


Manuscript Due Friday, 19 September 2014
First Round of Reviews Friday, 12 December 2014
Publication Date Friday, 6 February 2015


Genetic diseases are widely studied for the relevant impact on the human health. In the last years, a large amount of experimental data has been available. The identification of new strategies for elaborating such experimental data is becoming more and more necessary since the large amount of information can sometimes represent a real obstacle for the effective identification of relevant findings. The aim of the special issue is to review the recent advances about the research on computational methods concerning with genetic diseases. Potential topics include, but are not limited to:

Computational and mathematical methods for the following:
- Evaluating the pathogenicity of novel genetic variants
- The evaluation of protein folding and/or protein-protein interactions in presence of genetic variants
- Analysis of experimental data from next generation sequencing
- Searching for variant/mutation databases for massive data analysis
- Analysis of "omics" data
- Analysis of complex diseases, namely, multifactorial and polygenic, for example, diabetes, hypertension and dyslipidemia
- Variant analysis from Genome Wide Association studies
- Analysis of common genetic variants (i.e., SNPs, HLA genotypes, microsatellites)
- Analysis of quantitative trait loci
- The integration of genetic and non genetic factors for prediction of disease predisposition
- The identification of potential gene regulatory elements (i.e., binding of transcription factors, and miRNAs)
- Analysis of gene expression data
- Analysis of biological models of genetic diseases

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/cmmm/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/cmmm/genet/

URL: http://www.hindawi.com/journals/cmmm/si/828505/cfp/

Contact Person: Antonino Staiano (antonino.staiano@uniparthenope.it)
URL: http://www.hindawi.com/journals/cmmm/si/828505/cfp/

Contact Person: Antonino Staiano (antonino.staiano@uniparthenope.it)

Thursday, August 21, 2014

Biomathematics: the great frontier of the 21st century?

Some argue that by 2100 biology and mathematics will have changed each other dramatically.

Once upon a time, biology meant zoology and botany, the study of animals and plants. The invention of the microscope shifted the emphasis to the level of cells, and more recently the focus has been at the molecular level. Traditionally, the life sciences were attractive for young people who were passionate about science but who disliked mathematics or felt they were not good at it. But mathematics now plays a vital role in biology, and students need mathematical skills.

Biological systems are hugely complex, but simple mathematical models can isolate and elucidate key elements and processes and predict crucial aspects of behaviour. Many problems in biology have been solved using mathematics already developed in other areas – network analysis, group theory, differential equations, probability, chaos theory and combinatorics – but completely new mathematical techniques may be required to solve some tough problems in the life sciences.

The shape of a protein is an essential factor in determining its functions. For example, haemoglobin has a complex folded shape that enables it to "pick up" an oxygen molecule and "drop it" where it is needed. The folding and tangling of protein molecules is being modelled using the branch of topology called knot theory.

Network analysis shows us that a large network of simple components – whether transistors or neurons – can exhibit astonishingly complex behaviour. The human brain has 100 billion nerve cells, linked together by a biological wiring system of axons and dendrites. The number of interconnections is vast, something like a thousand million million. This is "big data" with a vengeance.

One simple element can do little. Link a large number together and you can get fantastically complex behaviour. For the brain, this includes thinking. Many questions in neuroscience remain to be answered, such as "how does memory work?" How is information from the senses interpreted and stored? Bio-informatics deals with the enormous data sets produced in biological research.

Systems biology is a rapidly developing interdisciplinary field of biological research. It focuses on complex interactions using a holistic approach aimed at discovering and understanding emergent properties of organisms. Such properties are difficult or impossible to understand using a reductionistic approach – breaking them down into basic constituents. Systems biology makes extensive use of mathematical and computational models.

The communication networks in the human body involve millions of interlinked cells. Occasionally, these networks break down, causing diseases such as cancer. Systems Biology Ireland, at UCD, is designing new therapeutic approaches based on a systems-level, mechanistic understanding of cellular networks. Researchers at Systems Biology apply mathematics and computer science to enormous data sets arising from biological techniques. Their research aims to find out what genes do, how they work together, what goes wrong in diseases, and how to cure them.

Just as astronomy gave rise to spectacular developments in mathematical analysis in the 18th century, biology may have a profound effect on mathematics in the future. Some commentators see biomathematics as the great frontier of the 21st century, and argue that by 2100 biology and mathematics will have changed each other dramatically, just as mathematics and physics did in earlier centuries.

Peter Lynch is professor of meteorology at University College Dublin. He blogs at thatsmaths.com
URL: http://www.irishtimes.com/news/science/biomathematics-the-great-frontier-of-the-21st-century-1.1898160

Contact Person: Peter Lynch (peter.lynch@ucd.ie)

Why biosciences and engineering are on a collision course

USC goes all in on convergent bioscience, bringing scientific curiosity and engineers' know-how to solve medical problems.

The world has become an enormously complex place. In 1790, the U.S. Patent Office opened its doors, and it took 103 years for the office to issue its first half-million patents. Now it issues far more than that in a single year.

And this acceleration toward complexity isn't just about patents — it's also about the science that drives them. That's especially pronounced in biomedicine. A century ago, a physician was everything in a town. He (or she) would deliver babies, dispense medication to the ill and even tend to a dog's broken leg. Today, doctors are so specialized they can be experts on a disease like cancer, for example, in only certain parts of the body, such as the bones, in a specific segment of the population, like children. They may do research too.

That specialized knowledge has led to big advances, but there's a flip side: These highly specialized scientists risk becoming so isolated that they might miss suggestions from others that could turn dead ends into new, promising research directions. It turns out that as our explorations peel away an ever-more intricate world, the connections between experts with wide-ranging perspectives become more vital. At USC, a movement is underway to bring together bioscientists and engineers to make the next generation of great leaps. It's called convergence, and it melds three fields: life science, physical sciences and engineering.

Society needs convergent research to move innovation forward and fix difficult challenges, but greater coordination is needed, according to a 2014 report from the National Research Council. It's going to take a culture shift for universities.

To understand how we got here, it helps to look to the past. The world of biology used to be rather flat, says Susan Forsburg, professor of biological sciences at the USC Dornsife College of Letters, Arts and Sciences. Biologists mostly studied how living organisms looked and behaved, and didn't have a clear way to "get under the hood" to examine the molecular mechanisms that explained those behaviors. But during World War II, physicists got involved and shook up the field. They became interested in the mechanics of DNA.

In 1953, physicist Francis Crick teamed up with James Watson to crack the structure of DNA. Driven by new ideas, scientists then figured out how DNA works, changing biology forever and giving rise to an entirely new field: molecular biology.

"Biology quickly went from observational science to something that used quantitative molecular approaches," Forsburg explains. The understanding of disease shifted dramatically as well. To cure someone of a disease, it became necessary to take that illness apart, cell by cell and gene by gene.

More recently, a genomics revolution has swept the sciences since the first map of the human genome was published in 2001. Sequencing an organism's entire genome and pinpointing sequence differences has offered insights into the foundation of many diseases and suggested potential solutions.

"The Human Genome Project gave us a parts list for understanding living systems, and what we want to do now is understand what the instruction manual looks like," says Steve Kay, dean of USC Dornsife.

Engineers have started bringing their own knowledge and skills to biological research as well. Take nanotechnology, which spurred new tools and understanding of the world on a tiny scale. Researchers have already created teeny particles that deliver drugs to targets inside the body. They're even exploring using nanosponges to stop internal bleeding.

The stage is now set for the next wave of change, melding engineers, molecular biologists and geneticists. Researchers call this wave convergence, and it relies on specialists working side by side. "The way you approach a problem is a team atmosphere, and the tools are new, so it can't be effective through virtual connections between people," Kay says. "Convergence needs a venue to be effective—a venue for really smart scientists and engineers to approach problems that are relevant to medicine."

USC in 2103 recruited biologist and interdisciplinary bridge-builder Scott Fraser from Caltech to help bring these experts together as director of science initiatives within the USC Office of the Provost. He's uniting physicists and engineers, computational biologists and chemists, and that's just for starters. Already, he and fellow faculty have begun bringing in the latest scientific equipment — including one of the world's most powerful experimental microscopes — that they'll all share, whether they come from biology, engineering or another field.

The new faculty, new equipment and new cooperation are evidence that the age of scientific silos is over. Forsburg, for one, relishes it, and she's quick to cite another example of convergence from her discipline of biological sciences.

"If you look at the acronym MCB at USC, here that stands for 'molecular and computational biology,'" she says. "Our math-oriented colleagues help us make sense of those big data sets. We're always looking for anything that mixes the pot and makes great synergy possible."

It hasn't always been easy to cross-pollinate different arenas of science. Mark Thompson, a chemist and materials scientist at USC Dornsife and USC Viterbi School of Engineering, says that when he started his career in 1987, scientists strived to be the sole authors on research papers. Forget collaborating with peers in your department, much less with researchers in other fields across campus. "Fortunately, we've moved away from that model," he says.

With researchers today more open to working together, big ideas from one scientific field can quickly translate into others, says Michael Quick, executive vice provost and professor of biological sciences. "I think we're about to see an increase in the number of practical solutions to problems coming at a faster rate," he says.

Part of the challenge is time and communication, Quick says. Physicians might have ideas that could help scientists, but they're busy with patients. And scientists and engineers aren't aware of the essential problems physicians need to solve.

But Yannis C. Yortsos, dean of USC Viterbi, says that the explosive pace of science and engineering has radically transformed all fields, including medicine. More than ever before, experts are working together to condense the time between scientific discovery, technology development and its application. "In the past, it took a long time for something to become useful," Yortsos says. "Today, the distance between the discovery of a phenomenon and its leveraging for useful purposes has shrunk dramatically. This is particularly important for interdisciplinary work, where people work and innovate closely together."

Take the artificial retina, for example. The implanted device helps restore vision. Led by University Professor Mark Humayun, a team of engineers, ophthalmologists, computer scientists and biologists from USC, other universities and industry have come together to invent, test and perfect the device.

The researchers had to bridge cellular biology — necessary for understanding how to stimulate retinal cells without permanent damage — with microelectronics, which led to the miniaturized, low-power integrated chip that converts signals and stimulates the cells. The hardware had to work seamlessly with software processing and tuning algorithms, and the whole package had to operate inside the eye. Then the team had to figure out how to surgically integrate the device inside the body, making sure that its 1,000 electrodes were placed in the exact spot in the eye only 6 millimeters across.

The U.S. Food and Drug Administration approved the device in 2013, and physicians are now implanting it into patients.

Finding clean and sustainable energy. Fighting disease. Feeding a growing world population. Which of these problems might convergence begin to solve? Perhaps all of them, and more.

Thompson already lives out the movement every day. With his USC Dornsife and USC Viterbi colleagues, he's used chemistry and engineering to create a way to light up smartphone screens four times more efficiently than ever — a technology now used by Samsung. He's also working on lightweight, portable solar energy cells. Yet he's just as excited about the potential for convergence to boost human health.

"We're almost at the point where we can sequence someone's genes and identify the best drug based on the person's genetic makeup," Thompson says. "So, as we understand the human body better, it's going to lead to revolutionary things."

Convergence will usher in a new generation of investigators who are uniquely prepared to work together and tackle challenges. "The students, both graduate and undergrads, they're not going to think of themselves as a chemist or a biologist," Kay says. "They're going to think of themselves as a problem-solver."

This story originally appeared in the summer 2014 issue of USC Trojan Family Magazine.
URL: http://www.news.usc.edu/67061/why-biosciences-and-engineering-are-on-a-collision-course/

Contact Person: Katharine Gammon (kategammon@gmail.com)

Tuesday, August 19, 2014

Call for Nominations--2015 Alan T. Waterman Award

2015 Alan T. Waterman Award

~ The National Science Foundation's Highest Honor ~

Call for Nominations http://www.nsf.gov/od/waterman/nsf_watermanaward_2015callfornominations_140806.pdf

Deadline: October 24, 2014

The National Science Foundation is pleased to accept nominations for the 2015 Alan T. Waterman Award. Each year, the Foundation bestows the Waterman Award to recognize the talent, creativity, and influence of a singular young researcher. The award consists of a $1,000,000 prize, a medal, a certificate, and a trip for two to Washington, DC, to receive the award. For details about the Waterman Award's history, the nomination procedure and the selection criteria please visit http://www.nsf.gov/od/waterman/waterman.jsp.

Nominees are accepted from any field of science or engineering. Nominations must be submitted electronically using NSF's FastLane system at https://www.fastlane.nsf.gov/honawards/index.jsp.

Please direct all inquiries about the award and the nomination procedures to Mayra Montrose (mmontros@nsf.gov).
URL: http://www.nsf.gov/od/waterman/waterman.jsp.

Friday, August 15, 2014

Global Collaboration Creates First Publicly Available Illumina HiSeq X Ten DNA Sequence Dataset

Australia's Garvan Institute, DNAnexus, and AllSeq sponsor sharing of sample dataset to educate the scientific community about the potential for world's most powerful DNA sequencing platform

August 07, 2014 01:21 PM Eastern Daylight Time
SYDNEY & MOUNTAIN VIEW, Calif. & LA JOLLA, Calif.--(BUSINESS WIRE )--The Garvan Institute of Medical Research, DNAnexus, and AllSeq, today announced that they are sponsoring free access to the world's first publicly available datasets generated using the Illumina HiSeq X Ten DNA sequencing platform. The goal for this project is to provide researchers with sample data that will allow them to gain a deeper understanding of what this technological advancement might mean for their work today and in the future.

"The tremendous advances in both volume and cost of whole genome sequencing using the Illumina HiSeq X Ten platform provides an exciting and practical avenue that moves us closer to the clinical translation of genomics"

The Garvan Institute's Kinghorn Centre for Clinical Genomics in Sydney, Australia, was one of the first three organizations in the world to acquire the Illumina HiSeq X Ten sequencing system. In an effort to enable the scientific community to assess data quality from an independent laboratory, they have made reference datasets available for a world first HiSeq X Ten data sharing project.

DNAnexus, an enterprise solution for genome informatics and data management, has sponsored the data storage and downloading support. The company also ran analyses to produce quality metrics to help the scientific community understand the results. AllSeq, which created the Sequencing Marketplace for matching DNA researchers and their needs with next generation sequencing service providers, arranged this data sharing endeavor as a part of its effort to educate scientists about different sequencing technologies and what they are suitable for.

"The tremendous advances in both volume and cost of whole genome sequencing using the Illumina HiSeq X Ten platform provides an exciting and practical avenue that moves us closer to the clinical translation of genomics," said Associate Professor Marcel Dinger, Head of Clinical Genomics and Genome Informatics at the Garvan Institute. "Advancing genomic medicine remains an international and highly collaborative effort and the Kinghorn Centre for Clinical Genomics is pleased to be working with DNAnexus and AllSeq to make sample data available to clinicians and researchers so that they can gain a deeper understanding of how this powerful technology may impact their work."

To develop the sample datasets, Garvan scientists used the Coriell Cell Repository NA12878 reference sample, which has been extensively analyzed by the Genome in a Bottle Consortium. Two different, high quality datasets are provided (NA12878D and NA12878J), each of which was sequenced on a single lane of an Illumina HiSeq X patterned flow cell, achieving over 120 Gb of yield, with greater than 87 percent bases with quality greater than Q30 in just 2.8 days. Each dataset meets the minimum coverage and quality guaranteed by Illumina and is indicative of the potential for the Illumina HiSeq X Ten sequencing system.

As the study and application of genomic data expands and proliferates, its true promise hinges on the genomics community's collective ability to manage all these data —securely, collaboratively, and efficiently. At full capacity, the Illumina HiSeq X Ten platform generates one genome every 25 minutes. According to internal data, transferring the two test genomes used in this project from the Garvan Institute in Australia into the DNAnexus system took less than 50 minutes, demonstrating that the DNAnexus platform in conjunction with Amazon's AWS Cloud can keep up with the pace of genomics. The runs were then analyzed and instantly shared with Garvan's scientific team for review. Within hours, these data were made available to the global research community to view and download.

"The DNAnexus platform was designed to be a complete solution for genomics analysis and data management, helping to accelerate basic science and clinical breakthroughs by bringing diverse teams together around ever-growing genomic datasets. The HiSeq X Ten presents a further challenge and opportunity for genomics in the production and management of genomic data, and Garvan has shown that the cloud can rise to this challenge," said Richard Daly, CEO of DNAnexus. "With the rise of consortia in the genomics community, the inevitability of the cloud and its ability to leverage scientific collaboration is near term. We are pleased to be working with the Garvan Institute and AllSeq to host the world's first HiSeq X Ten data sharing project so the scientific community can take a closer look at results from the '$1000 genome'."

The original FASTQ files, as well as analysis results (BAM and VCF files) and quality metrics, were calculated using the tools FastQC and Picard, (e.g., MarkDuplicates, CollectInsertSizeMetrics, and CollectWgsMetrics), are available at http://allseq.com/x-ten-test-data .

Those with DNAnexus accounts can also access these data via the DNAnexus platform, where users are able to copy any of the files to their own DNAnexus projects for further downstream analysis. For more information, https://dnanexus.com .

About the Garvan Institute of Medical Research and its Kinghorn Centre for Clinical Genomics

The Garvan Institute of Medical Research is one of Australia's largest medical research institutions with more than 600 scientists, students and support staff. Garvan's main research areas are: Cancer, Diabetes & Metabolism, Immunology and Inflammation, Osteoporosis and Bone Biology, and Neuroscience. Garvan's mission is to make significant contributions to medical science that will change the directions of science and medicine and have major impacts on human health. The outcome of Garvan's discoveries is the development of better methods of diagnosis, treatment, and ultimately, prevention of disease. In 2012, Garvan established Australia's first purpose-built facility for undertaking clinical-grade genome sequencing and large-scale research projects. With the support from the Kinghorn Foundation, Garvan acquired an Illumina HiSeq X Ten Sequencing System in January, 2014. The Kinghorn Centre for Clinical Genomics (KCCG) researchers undertake collaborat ive projects and genome-based studies to improve genome interpretation, with the ultimate aim of advancing the use of genomic information in patient care. KCCG is seeking accreditation that would ultimately allow clinicians to sequence genomes for diagnostic and therapeutic purposes. For more information please visit: http://www.garvan.org.au/

About DNAnexus

DNAnexus is powering the genomics revolution with an enterprise-level solution that combines cloud computing with advanced bioinformatics. The DNAnexus team is made up of experts in software, computational biology, and genetics who are on a mission to establish DNAnexus at the center of a growing ecosystem of scientific and clinical research, and diagnostic efforts in personalized medicine. For more information please visit: https://dnanexus.com .

About AllSeq

AllSeq has created the world's first true Sequencing Marketplace, which helps researchers fulfill their sequencing needs by matching them with the appropriate pool of sequencing providers. They provide free online tools for describing sequencing projects in an easy and systematic way, ensuring estimates are easy to compare and allowing researchers to pick the best provider (based on price, technology, turnaround time, etc). AllSeq also maintains the NGS Knowledge Bank, a neutral source of information on sequencing technologies, platforms and applications. For more information, please visit http://allseq.com .
URL: http://allseq.com/x-ten-test-data

Contact Person: Shawn C Baker (info@allseq.com)

Wednesday, August 6, 2014

The Federation of American Societies for Experimental Biology (FASEB)'s third annual BioArt competition

The Federation of American Societies for Experimental Biology (FASEB) is pleased to announce its third annual BioArt competition. Each day, scientific investigators product thousands of images and videos as part of their research, but very few are ever seen outside the laboratory. We are looking for visually compelling, high resolution submissions from federally-funded researchers and/or FASEB constituent society members. Images and videos can be submitted through August 30, 2014. For more information or to enter, please visit: www.faseb.org/bioart.

Please help us spread the word about this competition! Contact us at bioart@faseb.org if you would like a pdf flyer to share with others.
URL: http://www.faseb.org/About-FASEB/Scientific-Contests/BioArt.aspx

Contact Person: Joseph R. Haywood, PhD (bioart@faseb.org)

Friday, July 25, 2014

NPR Highlights Work of Robert Edwards, ISCB Member, Globe-Trotting Virus Hides Inside People's Gut Bacteria

Scientists at San Diego State University have discovered what may be the most common and abundant virus in the human gut. And yet, the tiny critter, called crAssphage (oh yes, there's a story behind that name), has eluded researchers' radar for decades.

The new virus doesn't make us sick, but it may be involved in controlling weight through its effect on Bacteroides. "We suspect this virus is very important in regulating the number of these bacteria [the Bacteroides] in the intestine," says computational biologist Robert Edwards, ISCB Member, who led the study.

URL: http://www.npr.org/blogs/goatsandsoda/2014/07/24/334089538/globe-trotting-virus-hides-in-people-s-gut-bacteria?utm_source=npr_email_a_friend&utm_medium=email&utm_content=20140724&utm_campaign=storyshare&utm_term=

Contact Person: ISCB Executive Office (executive.office@iscb.org)

Wednesday, July 23, 2014

Frontiers in Phylogenetics Symposium

The Washington DC Area Phylogenetics Consortium is pleased to announce the fourth annual Frontiers in Phylogenetics Symposium!

TITLE: "Genome-Scale Phylogenetics: Analysing the Data"

LOCATION: Warner Brothers Theatre, National Museum of
American History, Washington, DC

TIME & DATE: 9 AM to 5 PM, Monday September 15, 2014

REGISTRATION IS FREE BUT REQUIRED. Visit link below to register https://docs.google.com/forms/d/10p7xgDeAFOaVUHhxmQ6-fwf7E9N5lDJYfYf_PokQwmk/viewform?usp=send_form

John Kress - Acting Undersecretary for Science, Smithsonian Institution

Bastien Boussau, Laboratory of Biometry and Evolutionary Biology, University Claude Bernard, Lyon, France

Ingo Ebersberger, Department for Applied Bioinformatics, Goethe University, Frankfurt, Germany

Lacey Knowles, Department of Ecology and Evolutionary Biology and Museum of Zoology, University of Michigan, Ann Arbor, MI, USA

Kevin Kocot, School of Biological Sciences, University of Queensland, Brisbane, Australia

Luay Nakhleh, Department of Computer Science, Rice University, Houston, Texas, USA

David Swofford, Department of Biology, Duke University, and National Evolutionary Synthesis Center, Durham, NC, USA

Derrick Zwickl, Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, USA

The Frontiers in Phylogenetics Symposium is sponsored by the National Museum of Natural History, Smithsonian Institution and the Washington Area Phylogenetics Consortium. http://entomology.umd.edu/mitterlab/thewashingtonareaphylogeneticsconsortium

An updated announcement with talk titles and symposium schedule will follow soon.

Contact Person: Brian Coyle (coyleb@si.edu)

Bioinformatics Round Table Vienna meets ÖGMBT

Monday, September 15, 2014 at 09:50 a.m.
Vienna, Austria

The ÖGMBT, Austrian Society of Molecular Life Sciences and Biotechnology integrates molecular biology, biotechnology, and related disciplines starting from fundamental research towards applied science. Members of the ÖGMBT come from academic as well as industry organisations.

Connecting researcher and students, bridging gaps and enabling participants to share experiences and best practice is also today our goal, in the 'Special Edition' Bioinformatics Round Table Discussion meets ÖGMBT.

Keynote speaker: Amos Bairoch, University of Geneva, "New and Recurring Challenges in Biocuration"

Bioinformatics experts: Amos Bairoch, Bernhard Knapp, Christian Siehs, Christoph Bock, Andreas Kremer, Paul Perco, Andreas Heinzel, Klemens Vierlinger, and more ...

During our special session you will be able to meet and talk to biologists and bioinformatics experts which will provide an mutual exchange of views, understanding and scientific challenges. Among others we will be covering topics like sequencing and analysis, structural bioinformatics, computational systems biology, networks and functional analysis, biological knowledge discovery and data management.

Program of the 6th ÖGMBT Annual Meeting: http://xn--gmbt-4qa.at/jahrestagung/programm
Registration: http://xn--gmbt-4qa.at/jahrestagung/online-registration

URL: http://www.biosoftware.at/
Contact Person: T. H. Thuan Christine Huynh Buu  (thuan.huynhbuu@gmail.com)