Welcome to the ISCB Community News Blog

This blog collects news, announcements or other information which could be of interest to our ISCB members. We are a group ISCB members who volunteer to populate this blog on a regular basis. In case you want to become an "ISCB-News Reporter" yourself, let us know: contact ISCB
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Wednesday, December 18, 2013

OMICtools: An informative directory for HTS and array analysis

Dear All,

Current software and database resources for high-throughput sequencing (HTS) and microarray informatics are extremely fragmented. OMICtools (http://omictools.com) is a manually curated central directory that provides an overview of more than 1800 web-accessible tools related to HTS and microarrays.



URL: http://omictools.com

Contact Person: Arnaud Desfeux (arnaud.desfeux@gmail.com)

ISCB Congratulates Philip Bourne on Recent NIH Appointment

The International Society for Computational Biology (ISCB) congratulates past president and Fellow, Philip E. Bourne, Ph.D., on being selected as the first permanent Associate Director for Data Science (ADDS) at the National Institutes of Health (NIH). Dr. Bourne will start his new role at NIH in early 2014.

Dr. Bourne received his training as a physical chemist and his Ph.D. in chemistry from The Flinders University in South Australia, taking him to his current position at the University of California, San Diego, where he is the Associate Vice Chancellor for Innovation and Industry Alliances and a Professor in the Department of Pharmacology and Skaggs School of Pharmacy and Pharmaceutical Sciences. In addition, he currently holds the positions of Associate Director of the Research Collaboratory for Structural Bioinformatics (RCSB) Protein Data Bank and Adjunct Professor at the Sanford Burnham Institute.
"The creation of the ADDS position represents the commitment of NIH Director Francis S. Collins to a trans-NIH investment in advancing computational efforts and support in this age of biomedical research as an information science," said Jill P. Mesirov, Associate Director and Chief Informatics Officer at the Broad Institute of MIT and Harvard and member of the ISCB Board of Directors, who served on the NIH Advisory Committee to the Director's Data and Informatics Working Group. "Phil Bourne has long been involved in community efforts around this same goal. We all look forward to working with him and lending him our support as he takes on this critical role."
Dr. Bourne brings to NIH a professional focus on relevant biological and educational outcomes derived from computation and scholarly communication entailing algorithms, text mining, machine learning, metalanguages, biological databases, and visualization applied to problems in systems pharmacology, evolution, cell signaling, apoptosis, immunology and scientific dissemination.

As a founding board member of ISCB and president from 2002 – 2004, Dr. Bourne's vision and leadership has helped establish the Society which has greatly contributed to advancing the worldwide awareness and understanding of the science of computational biology. Dr. Bourne was named to the prestigious group of ISCB Fellows in 2011. Dr. Bourne is the co-founder and founding Editor-in-Chief of the open access journal PLOS Computational Biology. He has published over 300 papers and 5 books, selling over 150,000 copies. Dr. Bourne's professional focus has lended itself to a commitment to furthering the free dissemination of science through new models of publishing and better integration and subsequent dissemination of data and results which as far as possible should be freely available to all.

"ISCB is honored to have Phil's participation over the years," said Burkhard Rost, ISCB President. "We look forward to his future contributions to our fields as the Associate Director for Data Science at NIH."

About ISCB:
The International Society for Computational Biology (ISCB) - www.iscb.org - has been the first and continues to be the only society representing computational biology and bioinformatics on a worldwide scale. ISCB serves a global community of over 3,000 scientists dedicated to advancing the scientific understanding of living systems through computation. We convene the world's experts and future leaders in top conferences, we host the Intelligent Systems in Molecular Biology (ISMB) Conference, and we partner with publications that promote discovery and expand access to computational biology and bioinformatics. We deliver valuable information about training, education, employment, and relevant news. ISCB also provides an influential voice on government and scientific policies that are important to our members and benefit the public.

URL: http://www.iscb.org

Contact Person: Nadine Costello (ncostello@iscb.org)

Tuesday, December 17, 2013

Virtual Workshop on Bioinforma​tics from Bioclues (January 6-11, 2014)

The virtual workshop is aimed at research staff and those in the research community who fall under broader disciplines of Biotechnology.  Bioinformatics and systems biology will be catered to the inte....
URL: http://www.bioclues.org/joomla3/index.php/2-bioclues/11-courses-and-workshops
Contact Person: Prash Suravajhala  (news@bioclues.org)

The virtual workshop is aimed at research staff and those in the research community who fall under broader disciplines of Biotechnology.  Bioinformatics and systems biology will be catered to the interest of researchers. Hands-on sessions, a group discussion and a mini project at the end of the workshop will be done in the form of a group assignment. At the end of the workshop, the scientists are also invited to submit abstracts for presentation on the areas of their interest as talks in concurrent sessions, or as posters. Ample time will be set aside for discussion during the presentation of participants. The topics are then discussed with them for any collaboration for future virtual projects in Bioclues.org and also from the various collaborators of Bioclues across different countries.  This is a 20 hour taught programme interceded by 20 hours of home work plus mini project.

Networking points:

* Where is the NGS heading towards  bioinformatics research?

* Have we 'coded'  the genome?

* Ten simple steps to do bioinformatics research

* Whither programming?

* How's Modern Biology applied today?

* Does Bioinformatics really help us save time for wet-lab experiments?

More at events page of www.Bioclues.org

Thursday, December 12, 2013

FASEB Urges Congress to Support the Budget Deal Negotiated by Representative Paul Ryan and Senator Patty Murray

Bethesda, MD – The Federation of American Societies for Experimental Biology (FASEB) congratulates Representative Paul Ryan (R-WI) and Senator Patty Murray (D-WA) for reaching a bipartisan budget agreement for fiscal years (FY) 2014 and 2015. "The Ryan-Murray budget agreement represents a breakthrough in the Capitol Hill gridlock, recognizes the importance of providing additional funding for discretionary programs, and provides partial relief from sequestration. We are very grateful to Chairman Ryan and Chairwoman Murray for their hard work and willingness to compromise so that order can be restored to the budget process. We urge Congress to pass the agreement without any additional delay," said FASEB President Margaret K. Offermann, MD, PhD.

Passage of the Ryan-Murray agreement will also allow the Appropriations Committees to complete action on the unfinished FY 2014 spending bills. Failure to approve budgets for the federal research agencies in a timely manner impedes long term planning, disrupts research underway, and creates inefficiencies for institutions and individual scientists. "We sincerely hope that Congress will use the momentum created by the Ryan-Murray agreement to finally address the nation's long-term fiscal problems and adopt a plan that permanently replaces the indiscriminate cuts necessary under sequestration," stated Dr. Offermann. Over the next few weeks FASEB will be engaging the scientific community in reminding Congress about the benefits of providing sustained, predictable funding for the National Institutes of Health, the National Science Foundation, the Department of Energy Office of Science and competitive agricultural research supported by the U.S Department of Agriculture.

FASEB is composed of 27 societies with more than 110,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

URL: http://www.faseb.org

Contact Person: Lawrence Green (lgreen@faseb.org)

NIH Names Dr. Philip E. Bourne First Associate Director for Data Science

National Institutes of Health Director Francis S. Collins, M.D., Ph.D, announced today the selection of Philip E. Bourne, Ph.D., as the first permanent Associate Director for Data Science (ADDS). Dr. Bourne is expected to join the NIH in early 2014.

"Phil will lead an NIH-wide priority initiative to take better advantage of the exponential growth of biomedical research datasets, which is an area of critical importance to biomedical research. The era of 'Big Data' has arrived, and it is vital that the NIH play a major role in coordinating access to and analysis of many different data types that make up this revolution in biological information," said Collins.

Dr. Bourne comes to the NIH from the University of California San Diego, where he is the Associate Vice Chancellor for Innovation and Industry Alliances of the Office of Research Affairs and a Professor in the Department of Pharmacology and the Skaggs School of Pharmacy and Pharmaceutical Sciences. He also is the Associate Director of the Research Collaboratory for Structural Bioinformatics (RCSB) Protein Data Bank. Dr. Bourne was trained as a physical chemist and obtained his Ph.D. from The Flinders University in South Australia.

Dr. Bourne's professional interests focus on relevant biological and educational outcomes derived from computation and scholarly communication. This work involves the use of algorithms, text mining, machine learning, metalanguages, biological databases, and visualization applied to problems in systems pharmacology, evolution, cell signaling, apoptosis, immunology, and scientific dissemination. He has published over 300 papers and five books. One area to which he is extremely committed is to furthering the free dissemination of science through new models of publishing and better integration and subsequent dissemination of data and results.

Collins added, "I also must recognize and thank Dr. Eric Green, who served as the Acting ADDS since I announced the search to fill this new position. His willingness to take on this challenging role in its inception, and to get the ball rolling on the enormous tasks that accompany this high-priority initiative, is sincerely appreciated. Eric is certain to remain a tremendous source of knowledge and support as Phil continues the NIH's effort to manage 'Big Data'."

About the National Institutes of Health (NIH): NIH, the nation\\\'s medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit www.nih.gov.

URL: http://www.nih.gov

Contact Person: NIH Office of Communications (nihnmb@mail.nih.gov)

Tuesday, December 10, 2013

DREAM and Sage Bionetworks: Call for Challenge Participation


Dear Colleague,

The DREAM8.5 Challenges are now open:

1.The Alzheimer's Disease (AD) Big Data DREAM Challenge #1: Predict the best biomarkers for early AD-related cognitive decline, and the mismatch between high amyloid levels and cognitive decline. Open for registration.

2.The ICGC-TCGA DREAM Somatic Mutation Calling Challenge: Predict cancer-associated mutations from whole-genome sequencing data. Open for participation.

3.The Rheumatoid Arthritis Responder Challenge: Predict which patients will not respond to anti-TNF therapy. Open for registration.

Our DREAM8.5 Challenges, opening here at the tail end of DREAM8, respond to the shared mission that both DREAM and Sage Bionetworks have of using Challenges to accelerate the solutions to problems that matter to patients. The DREAM8.5 Challenges tackle important questions related to cancer, rheumatoid arthritis and Alzheimer's Disease. The traditional DREAM schedule of three-month long Challenges opening in the spring and completing in the fall seems insufficient to process the massive amount of data being generated in different disease areas that can be used in translational research. Help us journey forward as we strive to maintain DREAM's high level of excellence in systems biology while also welcoming new DREAMers to help us innovate and extend the wisdom of the crowds into new arenas of human health.

The 8.5 "Challenge season" has started and will wrap up in early Summer, 2014. Best performers from the 8.5 Challenges will be invited to co-author a Challenge-specific paper for submission to a scientific journal and to present their winning Challenge model at the 2014 DREAM conference (date and location to be determined).

To register for a Challenge, read details and get started, please go to https://www.synapse.org/#!Challenges:DREAM8.5


Gustavo Stolovitzky and Stephen Friend (co-chairs)
On Behalf of the DREAM8.5 Challenge Organizers

URL: https://www.synapse.org/#!Challenges:DREAM8.5

Contact Person: Gustavo Stolovitzky and Stephen Friend (dream8.5challenges@sagebase.org)

Monday, November 11, 2013

Call for application to the EMBO practical course on Bioinformatics and Genomes Analyses

Announcement and Call for Application to the EMBO practical Course on Bioinformatics and Genomes Analyses
( http://events.embo.org/14-comparative-genomics/index.html ) that will take place in the Hellenic Pasteur Institute, Athens, Greece, 5 – 17 May, 2014.

The main objectives of this Practical Course are to strengthen skills of PhD students and young researchers in the domain of Bioinformatics and Genome Data Analyses on the use of advanced fundamental algorithms and their applications in genome studies.

The course topics will include theoretical and practical aspects in:
- Genomes comparisons,
- Evolutionary analyses (orthologs, paralogs and ancestral genomes inference),
- RNAseq and Next Generation Sequencing (including algorithms, methods and sequence mapping tools, data analyses and applications).

The course programme will be centred on theoretical presentations followed by practical sessions. Practical sessions in a Linux environment will involve Unix shell and Perl scripting. Participants are assumed to be familiar with this environment.

A series of lectures delivered by prominent scientists on recent hot topics in genome (Giant Viruses, Prokaryotes, Eukaryotes) studies will be included in the programme and future research perspectives will be highlighted.

The topics that will be included in the course programme are similar to those included in previously organized courses: http://www.pasteur.fr/~tekaia/BGA_courses.html

The course is aimed at motivated Ph.D students and Post-Doctoral Researchers in Academic Institutions, with background in Mathematics, Statistics, Biology or Computer Science and who are involved in Bioinformatics and Genomes studies.

Selection of participants will be based on their background, running research projects and on expressed motivations.
Selected students will have free accommodation and meals and are expected to contribute with 200 euros and to pay for their travel expenses.
All participants (students and invited speakers) will stay in the same hotel.

Detailed indications are available on the course web site: http://events.embo.org/14-comparative-genomics/index.html

Candidates are advised to complete carefully the application form, together with an abstract of at least one of their running projects, a one-page CV and a personal Identity Picture (Photo).

The application deadline is March 14, 2014.

The organizers:
Menelaos Manoussakis, Hellenic Pasteur Institute, Athens, Greece.
Evdokia Karagouni, Hellenic Pasteur Institute, Athens - Greece.
Evie Melanitou, Institut Pasteur Paris - France.
Fredj Tekaia ( Institut Pasteur Paris France)
URL: http://www.pasteur.fr/~tekaia/BGA_courses.html

URL: http://events.embo.org/14-comparative-genomics/index.html

Contact Person: Fredj Tekaia (tekaia@pasteur.fr)

Friday, November 1, 2013

The 9th Georgia Tech - Emory University International Conference: Early Registration Closes October 15th!

The 9th Georgia Tech - Emory University International Conference:

"Genome Biology and Bioinformatics" will be held in Atlanta, Georgia, November 7-9, 2013

features an unlikely collection of high profile speakers: http://bioinformatics.gatech.edu/2013

The conference is the 9th in the biennial series started in 1997, the year when the word Bioinformatics was just coined.

The Bioinformatics conferences at Georgia Tech and Emory have been traditionally academic forums bringing together leading researchers in genomics, bioinformatics and genome biology.

... and Atlanta in November is a good place to be.

For more information go to URL: http://bioinformatics.gatech.edu/2013

Contact Person: Mark Borodovsky (borodovsky@gatech.edu)

ISCB Society Pages - Enjoy the Recently Published Articles

ISCB Society Pages in PLOS Computational Biology

View these two new articles in the right-hand column under Message from ISCB!

Explain Bioinformatics to Your Grandmother!
Virginie Bernard, Magali Michaut

APBioNet—Transforming Bioinformatics in the Asia-Pacific Region
Asif M. Khan, Tin Wee Tan, Christian Schönbach, Shoba Ranganathan
URL: http://www.ploscompbiol.org/home.action

Contact Person: Diane Kovats (dkovats@iscb.org)

Tuesday, October 22, 2013

The Significance of the 2013 Nobel Prize in Chemistry and the Challenges Ahead

The Significance of the 2013 Nobel Prize in Chemistry and the Challenges Ahead

By PLOS Computational Biology
Posted: October 18, 2013

Following the announcement of the 2013 Nobel Prize in Chemistry, PLOS Computational Biology Editor-in-Chief Ruth Nussinov discusses the implications of this award for both the computational biology and wider biological community.

Last week, the 2013 Nobel Prize in Chemistry was awarded to Martin Karplus, Michael Levitt and Arieh Warshel for "the development of multiscale models for complex chemical systems". As the Royal Swedish Academy of Sciences noted "Chemists used to create models of molecules using plastic balls and sticks. Today, the modelling is carried out in computers. In the 1970s, Martin Karplus, Michael Levitt and Arieh Warshel laid the foundation for the powerful programs that are used to understand and predict chemical processes. Computer models mirroring real life have become crucial for most advances made in chemistry today." Further, "Today the computer is just as important a tool for chemists as the test tube. Simulations are so realistic that they predict the outcome of traditional experiments."

This event is a milestone for the broad community that PLOS Computational Biology represents. Along with Philip E. Bourne, the Founding Editor-in-Chief, and our Editorial Board, which proudly lists Michael Levitt among its members, I extend the warmest congratulations to the winners. Beyond the specific personal scientific achievements that have already been widely discussed, we must consider the more general and broader context of this unique prize. Here, I would like to present this Nobel Prize within this framework, emphasizing its magnitude and far reaching implications not only for computational biology, but for the biological community at large.

In recent decades, molecular biology has progressed by leaps and bounds. Huge technological advances have taken place in sequencing, in mapping structure and dynamics via EM, X-ray and NMR, in manipulating imaging of nuclei and cells, in sequencing single biomolecules, and more. These have led to fundamental new insights; biology and medicine have soared to new heights with the DNA double helix providing the molecular basis for genetics and Darwinism. Many steps were required to identify and untangle DNA-RNA-protein sequence -structure- function and reverse transcription processes, RNA enzymes, key multi-partnered scaffolding molecules important under normal physiological conditions and in disease, their structures, mutations, and the principles and mechanisms of their dynamic regulation, and other landmark developments. These involved technological breakthroughs and greater understanding of the specific mechanisms involved. Most of the Nobel prizes in chemistry and medicine in recent years have been awarded at these junctures.

Vast amounts of information on sequences and structures are yet to be explained and pose a challenge for computational biology. Recently this has been compounded by interdisciplinary studies of the nervous system, posing questions such as how it is structured, how it develops, how it works, the mechanisms of signal processing, and more, all at multiple levels, ranging from the molecular and cellular levels to the systems and cognitive levels. Thus, even if we gain in-depth insight into static properties such as the genomic data and structural snapshots of proteins (DNA and RNA) at different levels of resolution, the truly monumental challenge of understanding their dynamics still looms ahead. And eventually, this is how cells, tissues and organisms develop and work.

The systems in question operate at all scales: force fields and free energy landscapes relevant for protein folding and function, large complexes, biomolecular recognition involving proteins, DNA, RNA, lipids, post-translational (and DNA) modifications, and interactions with small molecules. On a larger scale we see cellular locomotion, cell division and trafficking, and cell-cell recognition. Further, beyond these, lurks the working of the complex cell as a cohesive unit: the cellular network controls metabolism and regulation, intra- and inter-cellular signaling and the neural circuits of nerve cells, where the activity of one cell directly influences many others. All are dynamic, all change with the cellular environment and all present a daunting challenge. The relevant time scales range from femtosecond for simple chemical reactions to the eons of evolution; however, all operate with the same underlying physical principles of conformational variability and selection.

At each time scale and corresponding physical size we strive to identify the relevant moving parts and degrees of freedom and to formulate effective – though often approximate- rules for their mutual interactions and resulting motion. Solving, understanding, and computing the dynamic behavior at any given scale is of great interest in its own right and provides approximate dynamical input for the next scale, which is one rung above it. Only at the lowest, most basic scale of individual atoms and electrons are the dynamical rules (electrostatics and Schrödinger's equation) completely well defined. And the all-important work cited by the Nobel Prize Committee and which is carried out by our community is roughly at the first/second level, making it of fundamental importance.

This Nobel Prize is the first given to work in computational biology, indicating that the field has matured and is on a par with experimental biology. It may also be the very first prize given in any area of the exact sciences for calculations. What is different in the present case? I believe that the answer is simple: the present calculations are of much greater interest to a much broader community. In endeavoring to imitate the basic processes of life in silico, great strides are being made toward understanding the secret of life. Computational biology, and simulations, for which Martin Karplus, Michael Levitt and Arieh Warshel shared the Nobel Prize, can carry the torch leading the sciences to decipher the elemental processes and help alleviate human suffering.

What are the challenges ahead? Are simulations with time scales of microseconds, milliseconds or beyond, under the current force field framework, capable of producing results in agreement with experiment, also for large and complex proteins like membrane receptors? Do the challenges also lie in the type of questions which are asked, for which such long time scale simulations can be useful in providing answers? Or is it the biology behind the questions that is also the key? Ultimately, as in experimental biology which also exploits methods and machines, it is likely to be all of the above. Computations are our treasured tool; they are not our aim. Merely running long molecular dynamics trajectories is unlikely to advance science.

PLOS Computational Biology joins the International Society of Computational Biology (ISCB) and our computational biology community in congratulating the awardees and celebrating this momentous event.

URL: http://blogs.plos.org/biologue/2013/10/18/the-significance-of-the-2013-nobel-prize-in-chemistry-and-the-challenges-ahead/

Contact Person: ISCB Admin (assistant@iscb.org)

Tuesday, October 15, 2013

FASEB Rallies Research Community to Urge Congress to End the Government Shutdown

Bethesda, MD—The Federation of American Societies for Experimental Biology (FASEB) issued an e-action alert this week to the 110,000 members of its 27 constituent societies urging the public to call their elected representatives with a simple message—Congress must work together to end the government shutdown, restore funding for the National Institutes of Health, the National Science Foundation, and other science agencies to pre-sequestration levels, and agree on a fiscal year (FY) 2014 budget thatsustains the prior investment in research. "Until Congress agrees on an FY 2014 budget and supports the biomedical research enterprise, we continue to lose ground in every area of scientific research," stated FASEB President Margaret K. Offermann, MD, PhD. More than 300 phone calls were made in the first 24 hours after the alert was distributed. Researchers are being urged to recruit friends, family members, and neighbors in the effort to restore funding for research.

In conjunction with the e-action alert, FASEB is running targeted ads in selected media markets asking citizens to take action to protect the nation's investment in science and engineering. FASEB has also developed a talk radio guide providing instructions on how to effectively engage in local talk radio shows. The guide includes talking points about biomedical research funding and sequestration. "We must continue to urge Congress to support the federal science agencies," stated the FASEB President.

FASEB is composed of 27 societies with more than 110,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

URL: http://www.faseb.org

Contact Person: Lawrence Green (lgreen@faseb.org)

Thursday, October 10, 2013

Nobel Prize in Chemistry Awarded to Trio for Complex Computing Model

The Nobel Prize in Chemistry 2013 was awarded jointly to Martin Karplus, Michael Levitt and Arieh Warshel "for the development of multiscale computer models for complex chemical systems".

URL: http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2013/press.html

Contact Person: Diane Kovats (dkovats@iscb.org)

Tuesday, October 1, 2013

FASEB Announces Second Annual Stand Up For Science Video Competition

FASEB Announces Second Annual Stand Up For Science Video Competition

Bethesda, MD - The Federation of American Societies for Experimental Biology (FASEB) is offering a $5,000 prize for a short video to inform Americans about how federal agencies, such as the National Institutes of Health and the National Science Foundation, fund research throughout the country.

"Many Americans are unaware of the critical role the U.S. federal government plays in supporting biological research and discovery," stated FASEB President Margaret "Kenny" Offermann MD, PhD. "It is important that we do not lose sight of the research discoveries that have changed our lives, how they were achieved, and what could be next. We must continue our investment in science."

The competition opens today, October 1, and video submissions will be accepted through November 30, 2013. The winning entrant will be announced in February 2014. FASEB encourages individuals and groups from around the country to participate.

More information about the contest and the entry form can be found on the Stand Up For Sciencecompetition website. Last year's winning entry, "What's Next," underscored the importance of federal funding to science and technology, and highlighted the adverse consequences of spending cuts on innovative research.

FASEB is composed of 27 societies with more than 110,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

URL: http://www.faseb.org

Contact Person: Lawrence Green (lgreen@faseb.org)

Tuesday, September 24, 2013

Research Community Continues to Feel the Impact of Sequestration As More Cuts Loom

Catastrophic cuts to life saving biomedical research will continue unless Congress reaches agreement on an alternative approach to deficit reduction that cancels sequestration. According to a new factsheet released today by the Federation of American Societies for Experimental Biology (FASEB), the funding capacity of the National Institutes of Health (NIH) could be reduced by more than one-third (37 percent) compared to its 2003 level under the budget plan approved by the House earlier this year.

"Sequestration deals a devastating blow to an enterprise already suffering from underfunding and previous budget cuts, and the impact is being felt in labs and research institutions across the country," said FASEB President Margaret "Kenny" Offermann, MD, PhD. "We've seen critical research scaled back, trainees lose jobs, and senior investigators leave the field. The situation is undermining our prior investment in research. This does not have to happen."

Since 2003, flat-funding, inflation, and $1.7 billion in cuts due to sequestration have reduced NIH's ability to support innovative research. Today, NIH can fund only one in six grants, leaving many excellent research programs without support and risking the U.S.'s role as a leader in biomedical research. "The scientific opportunities to develop new therapies for many diseases are unprecedented but we will not make progress if we keep cutting funding for NIH. It is time for Congress to enact a bipartisan plan that reduces the deficit in a meaningful way and replaces sequestration, once and for all," commented Dr. Offermann.

FASEB is composed of 27 societies with more than 110,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

URL: http://www.faseb.org

Contact Person: Lawrence Green (lgreen@faseb.org)

2014 Alan T. Waterman Award -- Call for Nominations

~ The National Science Foundation's Highest Honor ~

Call for Nominations (Deadline: October 25, 2013)

The National Science Foundation is pleased to accept nominations for the 2014 Alan T. Waterman Award. Each year, the Foundation bestows the Waterman Award to recognize the talent, creativity, and influence of a singular young researcher. The award consists of a $1,000,000 grant and a trip for two to Washington, DC, to receive the award. For details about the Waterman Award's history, the nomination procedure and the selection criteria please visit http://www.nsf.gov/od/waterman/waterman.jsp.

Nominees are accepted from any field of science or engineering that NSF supports. Nominations must be submitted electronically using NSF\\\'s FastLane system athttps://www.fastlane.nsf.gov/honawards/index.jsp.

Please direct all inquiries about the award and the nomination procedures to Mayra Montrose (mmontros@nsf.gov).
URL: http://www.nsf.gov/od/waterman/waterman.jsp

Contact Person: Mayra Montrose (mmontros@nsf.gov)

Monday, September 23, 2013

PLOS Computational Biology--Translational Bioinformatics: Call for papers

Following the successful launch of the PLOS Computational Biology collection 'Translational Bioinformatics', we are delighted to announce the continued development of this collection with a call for new articles.

The collection, which initially launched in December 2012, reads as book and is intended for use as a reference or tutorial for a graduate level introductory course on the science of translational bioinformatics. As a field, translational bioinformatics is rapidly evolving and our plan is to develop the content of the collection as the field develops. The collection editors Maricel Kann, Associate Editor, and Fran Lewitter, Education Editor, comment:

"We have been very pleased with the reception of the PLOS CB "Translational Bioinformatics" collection. It is being used as a text book in university courses and we have had requests to translate the collection into other languages to make it accessible to a wider audience. We are looking forward to adding chapters to the collection in other areas of translational bioinformatics and welcome your suggestions."

At present, the collection is made up of an introduction by Russ Altman and then 17 chapters, each crafted by leading experts in the field. Each of these 17 chapters focuses on a key topic, ranging from genome-wide association studies to text-mining, and provides a solid introduction for those new to the subject, complete with exercises and answers. Together these form an online reference tool, which, in an exciting new step for the journal, has been made available as an eBook in PDF, EPUB and MOBI formats.

We plan to publish new chapters twice-yearly, with the next round of new chapters aimed for February 2014. Articles will stand the best chance of inclusion in this release if they are submitted by 15 September 2013. Articles submitted after this date will be considered for the July 2014 release.

To submit an article: go to http://www.editorialmanager.com/pcompbiol/. Please note that prior to full submission, authors should submit a presubmission inquiry for consideration by the collection editors. We encourage authors to refer to the Author Guidelines, available here.

Please contact us at ploscompbiol@plos.org with any questions.

You can visit the collection at: www.ploscollections.org

URL: http://blogs.plos.org/biologue/2013/07/18/translational-bioinformatics-call-for-papers/

Contact Person: Mei Yan (mleung@plos.org)

Friday, September 6, 2013

WikiProject Computational Biology/ISCB competition announcement 2013

The International Society for Computational Biology (ISCB) announces an international competition to improve the coverage on Wikipedia of any aspect of computational biology. A key component of the ISCB's mission to further the scientific understanding of living systems through computation is to communicate this knowledge to the public at large. Wikipedia has become an important way to communicate all types of science to the public. The ISCB aims to further its mission by increasing the quality of Wikipedia articles about computational biology, and by improving accessibility to this information via Wikipedia. The competition is open to students and trainees at any level either as individuals or as groups.

The prizes provided by ISCB for the best articles submitted will be:

1st prize - $500 (USD) and 1 year membership to the ISCB.
2nd prize - $250 (USD) and 1 year membership to the ISCB.
3rd prize - $150 (USD) and 1 year membership to the ISCB.

For more information go to http://en.wikipedia.org/wiki/Wikipedia:WikiProject_Computational_Biology/ISCB_competition_announcement_2013
URL: http://en.wikipedia.org/wiki/Wikipedia:WikiProject_Computational_Biology/ISCB_competition_announcement_2013

Contact Person: Alex Bateman (agb@ebi.ac.uk)

Thursday, August 8, 2013

RECOMB 2014 ---- Call for Papers

RECOMB 2014: the 18th International Conference on Research in Computational Molecular Biology
April 2-5, 2014, Pittsburgh, PA
Submission open: September 2, 2013
Submission deadline: October 15, 2013
Submission entry: https://www.easychair.org/conferences/?conf=recomb2014
Conference website: http://www.compbio.cmu.edu/recomb/

The 18th International Conference on Research in Computational Molecular Biology (RECOMB 2014) will be held in Pittsburgh, PA on April 2-5, 2014. The RECOMB conference series was founded in 1997 to provide a scientific forum for advances in computational biology and applications in molecular biology and medicine. The conference aims at bridging the computational, mathematical, statistical, and biological sciences, and bringing together researchers, professionals, students and industrial practitioners from all over the world for interaction and exchange of new developments in all areas of bioinformatics and computational biology. The conference will feature keynote talks by leading scientists, presentations of peer-reviewed high-quality research papers, presentations of exciting research developments that were published within the past year and poster sessions on latest research progress.

Papers reporting on original research in all areas of computational molecular biology and bioinformatics are sought. Topics of interest include, but are not limited to:

• Molecular Sequence Analysis
• Regulation and Epigenomics
• Molecular Evolution
• Gene Expression
• Biological Networks
• Sequencing and Genotyping Technologies
• Metagenomics
• Population and Statistical Genetics
• Systems Biology
• Computational Proteomics
• Computational Structural Biology
• Bioimaging

Submissions will be reviewed by the Program Committee, and selected papers will be accepted for presentation at the conference. Accepted extended abstracts will be published as a proceedings volume in the Lecture Notes in Bioinformatics (LNBI) series by Springer-Verlag, which will be available at the conference. RECOMB 2014 is partnering with the Journal of Computational Biology (JCB). Accepted papers will be invited, but not required, to submit an edited journal version for a special issue of JCB.

Parallel Submission: RECOMB 2014 has teamed up with PLoS Computational Biology to allow for reviewing a selected set of papers for the journal in parallel to their consideration by RECOMB. Authors who wish their manuscript to be considered for publication in PLoS Computational Biology must clearly indicate this at the time of submission to RECOMB, and submit a complete manuscript for review. Manuscripts that are accepted to RECOMB will appear either as two-page abstracts or full papers in the LNBI proceedings depending on their review/acceptance status in PLoS Computational Biology. Full details can be found on the conference website. No other parallel submissions are allowed.

Key dates (Extended Abstracts)

Submission opens: September 2, 2013
Submission deadline: October 15, 2013
Acceptance notification: December 9, 2013
Final version due: January 16, 2014

Full details on manuscript preparation and submission procedures can be found on the conference website.

Best Regards,

Roded Sharan, Program Chair
Russell Schwartz, Conference Chair
URL: http://www.compbio.cmu.edu/recomb/

Contact Person: Russell Schwartz (tgulish@cmu.edu)

Friday, August 2, 2013


The White House announced that President Obama intends to nominate physicist Dr. France Anne Cordova to be the next NSF Director. We do not yet know when Dr. Cordova's nomination will be considered by the Senate. Dr. Cordova is President Emerita of Purdue University, where she served as President from 2007 to 2012. From 2002 to 2007, Dr. Cordova served as Chancellor of the University of California at Riverside, where she was a Distinguished Professor of Physics and Astronomy. Previously, Dr. Cordova was the Vice Chancellor for Research and Professor of Physics at the University of California at Santa Barbara from 1996 to 2002. She served as NASA's Chief Scientist from 1993 to 1996. She was on the faculty of the Pennsylvania State University, where she served as Head of the Department of Astronomy and Astrophysics from 1989 to 1993. Dr. Cordova served as Deputy Group Leader in the Earth and Space Sciences Division at Los Alamos National Laboratory from 1988 to 1989 an d Staff Scientist from 1979 to 1989. She is Chair of the Board of Regents of the Smithsonian Institution and a member of the National Science Board. Dr. Cordova received a B.A. from Stanford University and a Ph.D. from the California Institute of Technology.

In addition, American Society for Microbiology President Dr. Jo Handelsman was nominated to serve as Associate Director for Science in the White House Office of Science and Technology Policy. Dr. Handelsman has worked with the FASEB MARC program and will focus on issues related to medical innovation, biotechnology, physical sciences, and other areas. Dr. Jo Handelsman is the Howard Hughes Medical Institute Professor and Frederick Phineas Rose Professor in the Department of Molecular, Cellular and Developmental Biology at Yale University, a position she has held since 2010. Previously, she served on the University of Wisconsin-Madison faculty as a Professor in Plant Pathology from 1985 to 2009 and Professor and Chair of the Department of Bacteriology from 2007 to 2009. She is currently President of the American Society for Microbiology. In 2011, Dr. Handelsman received the Presidential Award for Excellence in Science Mentoring. From 2002 to 2010, Dr. Handelsman was the Direct or of the Wisconsin Program for Scientific Teaching. In 2004, Dr. Handelsman co-founded the National Academies Summer Institute on Undergraduate Education in Biology. She received a B.S. from Cornell University and a Ph.D. from the University of Wisconsin-Madison.

URL: http://www.whitehouse.gov/the-press-office/2013/07/31/president-obama-announces-more-key-administration-posts

Contact Person: Nadine Costello (assistant@iscb.org)

Update your bioinformatics paper as often as you update your software, with F1000Research

F1000Research is an online life science journal, which enables articles to be updated post-publication, through the use of versioned papers. The journal is waiving all charges for bioinformatics software papers submitted before 31st December 2013. This is great news for both developers and users of bioinformatics tools; as incremental improvements and updates to software are released, these can be documented through a set of F1000Research-threaded papers.

F1000Research is novel in many of its approaches to science publishing. Once an article has passed editorial checks, publication is very fast, typically under 7 days following final submission. Articles undergo formal transparent peer-review, post-publication, with all reviews and any resultant discussion being documented as part of the article. The journal also requires all papers to include the underlying data, and all good science is accepted, regardless of perceived impact at time of publication.

The threaded papers approach enables developers to minimize the time spent on the important (but time consuming) job of disseminating documentation, whilst also demonstrating to funding bodies a commitment to ongoing engagement with users. Furthermore, it shows users that a tool is being actively maintained and improved.

To encourage bioinformatics tool developers to try this new way of publishing, F1000Research are waiving all article processing charges for such life science software papers submitted before the end of 2013. The fee waiver includes subsequent updates; just put the code SOFT13 in Section 6 of the simple one-page submission form. If you are using LaTeX to write papers, there is also a one-click submission option from the F1000Research LaTeX template, hosted by the online collaborative LaTeX editor writeLaTeX.

So how about providing an F1000Research threaded publication for your bioinformatics tool, allowing you to update the paper as you improve your software?

More information about F1000Research can be found at http://f1000research.com/
More information about threaded software papers can be found at http://blog.f1000research.com/2013/07/22/document-your-software-updates-with-f1000research/
The writeLaTeX F1000Research template can be found at https://www.writelatex.com/templates/41-f1000research-journal-article-template

URL: http://f1000research.com/

Contact Person: Michael Markie (michael.markie@f1000.com)

Saturday, July 13, 2013

UberCloud Experiment now open to bioinformatics and computational biology

Now the UberCloud Experiment is open also to organizations focusing on bioinformatics and computational biology. The UberCloud Experiment started in mid-2012 with the aim of exploring the end-to-end process employed by digital manufacturing engineers and HPC experts to access and use remote computing resources in HPC centers and in the cloud. Since then the UberCloud HPC Experiment has achieved the volunteer participation of 500 organizations and individuals from 48 countries. Over 85 teams have been involved so far. Each team consists of an industry end-user and a software provider. The organizers match them with a well-suited resource provider and an HPC expert. Together, the team members work on the end-user's application with the mission of:

- Defining the resource and software requirements
- Implementing the application on the remote HPC system
- Running and monitoring the application job
- Getting the results back to the end-user
- And finally writing their case study

The Compendium is a selection of 25 case studies from the first 60 teams to raise awareness in the manufacturing, biology, and HPC community about the benefits and best practices of using remote HPC capabilities in HPC centers and in the cloud. This illuminating document is an invaluable resource for engineers, managers and executives who believe in the strategic importance of applying advanced technologies to help drive their organization's productivity to perceptible new levels.

The Compendium can be downloaded from http://tci.taborcommunications.com/UberCloud_HPC_Experiment
URL: http://tci.taborcommunications.com/UberCloud_HPC_Experiment

Contact Person: Wolfgang Gentzsch (wolfgang@hpcexperiment.com)

Wednesday, June 26, 2013

Pathview: pathway based data integration and visualization

Pathview is a newly released/published R/Bioconductor package for pathway based data integration and visualization. It maps and renders a wide variety of biological data on relevant pathway graphs. Pathview easily integrate with pathway and functional analysis tools for large-scale and fully automated analysis pipelines.

The pathview package was recently published in Bioinformatics:

The package is available through Bioconductor and R-Forge:
Please try it out and let me know if you have any comments/suggestions. Thank you!

URL: http://bioconductor.org/packages/release/bioc/html/pathview.html

Contact Person: Weijun Luo (luo_weijun@yahoo.com)

Monday, June 24, 2013

New Funding Opportunity for Computational Drug Discovery

The Alzheimer's Drug Discovery Foundation (ADDF) program is requesting proposals for innovative computational approaches to predict the efficacy of compounds to treat and prevent dementia. Details can be found at the associated URL.

The Alzheimer's Drug Discovery Foundation (www.alzdiscovery.org) is a not-for-profit donor-funded organization that seeks to rapidly accelerate the discovery of drugs to prevent, treat, and cure Alzheimer's disease, related dementias, and cognitive aging. We are the largest private funder of drug discovery for Alzheimer's disease in the world, currently funding research in academic and biotech organizations in 18 countries. We also provide research resources for drug discovery including conferences, workshops, advisory panels, and a network of CROs and consultants for drug discovery.

Please do forward this RFP to any researchers or organizations who may be interested in this funding opportunity.
URL: http://alzdiscovery.org/assets/content/static/RFP_for_Computational_Modeling_approved_May22.pdf

Contact Person: Penny Dacks (pdacks@alzdiscovery.org)

Thursday, June 20, 2013

Aviv Regev recently Named HHMI Early Career Scientist

Aviv Regev, associate professor of biology at the Massachusetts Institute of Technology and a core member of the Broad Institute of MIT and Harvard, was recently named a Howard Hughes Medical Institute (HHMI) investigator. Regev was among 27 biomedical scientists selected as new HHMI investigators from 1,155 applicants. According to HHMI, the initiative represents an investment in basic biomedical research of approximately $150 million over the next five years. This support gives HHMI investigators the freedom to explore new research directions.

Regev, an ISCB member since 2002, was awarded the ISCB Overton Prize in 2008. Her research centers on understanding how complex molecular networks function and evolve in the face of genetic and environmental changes, over time-scales ranging from minutes to millions of years. She was named an Early Career Scientist of the Howard Hughes Medical Institute in 2009 and is a recipient of the NIH Director's Pioneer Award and a Sloan fellowship from the Sloan Foundation.

ISCB congratulates Aviv on her recent achievements and on her selection to this distinguished group of researchers.

URL: http://www.broadinstitute.org/history-leadership/leadership/scientific-leadership/core-members/aviv-regev

Contact Person: ISCB Admin (assistant@iscb.org)

Wednesday, June 5, 2013

FASEB Responds to Criticisms of NIH Communications Expenditures

Bethesda, MD - Correspondence co-authored by FASEB leadership and staff that responded to criticisms of National Institutes of Health (NIH) communications expenditures was published in the May 30, 2013 issue of the journal Nature. Prompted by series of articles in The Cancer Letter in which spending by the National Cancer Institute (NCI) Office of Communications and Education (OCE) was criticized (also covered in Nature), the US Congress launched an inquiry into all "public relations" expenditures by the National Institutes of Health (NIH). In its response, FASEB emphasized the value of communications the NIH mission and that reduction of spending to these programs would provide virtually no relief to loss of capacity to fund research sustained by NIH as a result of sequestration, a decade of flat funding, and inflation.

In addition to the content of the Nature correspondence, FASEB would like to highlight the following additional points related to the inquiry of NCI OCE expenditures and spending by the NIH on communications efforts more broadly:

· Many NCI OCE activities are in response to Congressional mandates or requests.
· The NCI OCE produces many resources for cancer patients, doctors, researchers, and the American public including: educational brochures; the Physician Data Query, an online resource that provides peer-reviewed summaries on cancer research, treatment, care, and prevention, as well as a database of past and current clinical trials; and toll-free phone lines for cancer information and tobacco cessation.
· While some critics noted spending reductions at NCI OCE (by 34 percent since 2006 not adjusting for inflation), the cancellation of the NCI Cancer Bulletin in January 2013 was not acknowledged – further evidence that NIH leadership has and continues to address mission creep.
· FY 2013 cuts to the NIH budget due to sequestration (approximately six percent of the NCI budget) dwarf the less than one percent of the NCI budget devoted to NCI OCE expenditures in 2012. Further reductions in communications and education spending will not greatly improve the financial situation of NCI or NIH, but may make biomedical discoveries less accessible to the patients, physicians, and the public.
· This congressional inquiry came during a critical period in which the efforts of senior NIH staff members were diverted from portfolio planning to accommodate sequestration cuts to respond to the inquiry.

The value of science is exponentially increased when it is shared with and utilized by society at large. Therefore, FASEB strongly supports the efforts of the NCI OCE as well as related offices within other NIH Institutes and Centers (ICs), as communication with and education of the public is integral to the pursuit NIH's overall mission.
URL: http://www.FASEB.org

Contact Person: Lawrence Green (lgreen@faseb.org)

Tuesday, June 4, 2013

University of Texas researcher uses algorithm to simulate molecular movements in real time

A researcher at The University of Texas uses an algorithm called Milestoning to simulate the molecular movements of important biological molecules, like myosin and reverse transcriptase.

Ron Elber, a researcher at UT's institute for Computational Engineer and Sciences, uses Milestoning to simulate how molecules move in space and over time. The technique provides insights into important processes, which may be used in research across fields, especially in the area of drug development.

Milestoning also is an advancement from many computational approaches which can model atomic detail for only short time frames. Milestoning, on the other hand, can theoretically model molecular motions over any time frame.

URL: http://www.ices.utexas.edu/about/news/223/

Contact Person: Monica Kortsha (mkortsha@ices.utexas.edu)

Thursday, May 23, 2013


Bethesda, MD – The Federation of American Societies for Experimental Biology (FASEB) has released a new factsheet highlighting the value that federally funded biomedical and biological research provides to the American public as well as the private sector. The factsheet provides specific examples of National Institutes of Health (NIH) and National Science Foundation (NSF) funded research that leads to improved health, a strengthened the U.S. economy, and the development of new technologies, products, and industries. It also notes that the private sector depends on federal funding for basic research to create the knowledge necessary to support applied research.

FASEB encourages the scientific community to share this factsheet with members of Congress during the upcoming Memorial Day recess (May 27 – May 31). "We must remind our elected officials that publically and privately funded research are complementary, not interchangeable," said FASEB President Judith S. Bond, PhD. "Yesterday, the House Appropriations Committee approved spending limits that could cut fiscal year 2014 funding for NIH nearly 20 percent below the sequestration level and further reduce the budget for NSF. Additional cuts to the NIH and NSF budget will hurt our quality of life and severely undermine U.S. innovation and development."

FASEB is composed of 26 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.
URL: http://www.FASEB.org

Contact Person: Jennifer Zeitzer (jzeitzer@faseb.org)

Monday, May 20, 2013

CFP: 2013 Computational Structural Bioinformatics Workshop (CSBW)

The 2013 Computational Structural Bioinformatics Workshop will be held in conjunction with ACM-BCB. The rapid accumulation of macromolecular structures presents a unique set of challenges and opportunities in the analysis, comparison, modeling, and prediction of macromolecular structures and interactions. This workshop aims to bring together researchers with expertise in bioinformatics, computational biology, structural biology, data mining, optimization and high performance computing to discuss new results, techniques, and research problems in computational structural bioinformatics.

CSBW invites high quality original papers and posters on developments in computational problems relating to molecular structure. Authors of accepted papers will be provided approximately 20 minutes to provide an oral summary of their work, with time for questions. Please refer to website above for details about format and submission. At least one author of an accepted paper is required to register for the workshop to present the paper. Registration to CSBW is complementary with registration to ACM-BCB 2013.

Important dates:
June 28, 2013: Paper submission deadline
July 24, 2013: Notification of paper acceptance
August 1, 2013: Camera-ready paper submission deadline
September 5, 2013: Poster abstract submission deadline
September 22-25, 2013: workshop/ACM-BCB conference

The CSBW Co-Chairs are also very pleased to announce that Lenore Cowen, of the Department of Computer Science at Tufts University, will present the Keynote Lecture at our workshop.

Submitted manuscripts should not exceed 10 pages in ACM template on 8.5 x 11 inch paper (see ACM templates). All the manuscripts should be submitted at http://www.cse.buffalo.edu/ACM-BCB2013/submission.html. All accepted papers will be published in proceedings published by ACM digital libraries. Journals used in previous years included the International Journal of Data Mining and Bioinformatics (2007), BMC Structural Biology (2009, 2012) and the Journal of Bioinformatics and Computational Biology (2011).

CSBW also seeks poster abstracts on developments or significant works in progress towards computational problems relating to molecular structure. Posters sessions will expand scientific dialogue at the workshop and train students in scientific communication. Authors of accepted posters will have unhurried opportunities to communicate their results in poster sessions taking place during the day.

Possible topics include, but are not limited to:
- Structure representations
- Structure prediction and refinement
- Structure comparison and alignment
- Molecular interaction, docking, and simulation
- Coarse-grained modeling
- Mining structural data
- Structural genomics
- Applications of high performance computing to structural problems
- Applications of graph theory and optimization to structural problems
- Structure-based drug design
- Biomolecular graphics

Workshop Chairs:
Jing He, Department of Computer Science, Old Dominion University
Amarda Shehu, Department of Computer Science, George Mason University
Nurit Haspel, Department of Computer Science, University of Massachusetts, Boston
Brian Chen, Department of Computer Science and Engineering, Lehigh University

Contact: For questions regarding the workshop, please email jhe@cs.odu.edu

URL: http://www.cs.odu.edu/~lchen/CSBW.htm

Contact Person: Brian Chen (chen[removethis]@lehigh.edu)

Wednesday, May 15, 2013

Summer School on (Meta)Genomics and Molecular Epidemiology

The CSISP Summer School is addressed to graduate students, professionals and practitioners of biomedical research, public health and other biological and health sciences. This 3rd CSISP Summer School edition will focus on the area of Genomics and Health, with a strong hands-on component and direct experience of the application of genomic science in a Public Health research center. The school will consist of 5 independent modules that may be taken individually and will include theoretical lectures, research seminars, and practical sessions. The summer school will take place at the Center for Public Health Research (CSISP) of the Valencian Health Department and will be taught in English by CSISP researchers and by invited professors from leading international institutions.
URL: http://www.csisp.gva.es/en/summer-school

Contact Person: Beatriz Chacartegui (summerschool_csisp@gva.es)

Wednesday, May 8, 2013

PLOS Computational Biology Announces 2013 T-shirt Design Competition

PLOS Computational Biology Announces 2013 T-shirt Design Competition

For more information please go to:
URL: http://www.plos.org/

Contact Person: Clare Weaver (ploscompbiol@plos.org)

Thursday, May 2, 2013

ISCB-Asia/SCCG 2012 BMC Genomics Special Issue Complete

The BMC Genomics Special Issue for the proceedings track of ISCB-Asia/SCCG 2012 is now complete. Nine original research papers and an introduction covering all talks given at the conference.
URL: http://www.biomedcentral.com/bmcgenomics/supplements/14/S2

Contact Person: Paul Horton (paulh@iscb.org)

Thursday, April 25, 2013


Bethesda, MD: The Federation of American Societies for Experimental Biology (FASEB) is pleased to announce its release of the latest edition of the Breakthroughs in Bioscience series: "Conquering Cancer with Drugs from Nature's Medicine Cabinet". Also available as a downloadable podcast, the article is the second of a two-part series that discusses the basic research foundations of the development of natural product-derived medicines (see part one here) and specifically focuses on cancer treatments.

In 1992, the Food and Drug Administration's (FDA) approval of Taxol, which derives from the Pacific yew tree, increased the five-year survival rate of metastatic ovarian cancer patients from 20 to 80 percent.  More recently, seven anti-cancer drugs resulting from natural compounds were approved by the FDA, while seven more are currently in the drug-development pipeline.

The Breakthroughs in Bioscience series is a collection of illustrated articles, published by FASEB, that highlight the recent developments in basic biomedical research and explain how they impact medicine and human health. To obtain free copies of these publications, visit the FASEB Breakthroughs in Bioscience web site at http://www.faseb.org/break-throughs or contact FASEB's Office of Public Affairs at 301.634.7650.

FASEB is composed of 26 societies with more than 100,000 members, making it the largest coalition of biomedical research associations in the United States. Our mission is to advance health and welfare by promoting progress and education in biological and biomedical sciences through service to our member societies and collaborative advocacy.

Contact Person: Lawrence Green  (lgreen@faseb.org)